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2010, Number 3

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Rev Mex Anest 2010; 33 (3)

Influence of nitrous oxide at 2,240 m over the sea level in the dose of propofol used for anesthesia induction

Martínez-Ara MF, Pórtela-Ortiz JM, Rivera-Orna MÁ, Rendón-Macías ME

Language: Spanish
References: 15
Page: 142-146
PDF size: 330.85 Kb.


ABSTRACT

Introduction: Nitrous oxide (N2O) was used for over 150 years for its analgesic, ansiolytic and anesthetic. This study seeks to demonstrate that the use of N2O lower the dose of propofol during induction of anesthesia, at the height of Mexico City. Methods: A randomized, prospective and comparative study. We studied patients undergoing general were divided into groups: group A received 6 liters of oxygen, group B 4 liters of N2O and 2 liters of Oxygen per minute, reaching a concentration of exhaled N2O 65%. We applied propofol at 20 mg per minute and assesses the loss of reflexes: verbal, handles and lid in seconds and the dose of propofol. Results: Demographic variables were not differences. Group A patients required a dose greater than 65% of propofol and the time was 54% higher for the loss of reflexes in relation to the group which use N2O - propofol. Conclusions: Nitrous oxide is useful as an anesthetic at the height of 2,240 meters above sea level. Significantly reduces the dose of propofol during induction of anesthesia.


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