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Colegio de Medicina Interna de México.

2009, Number 1

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Med Int Mex 2009; 25 (1)

Correlation of body water with insulin resistance in elderly

Mendoza RMA, Ramírez AMC, González RMV, López EF, Medina JJJ, Ortega BOO

Language: Spanish
References: 14
Page: 17-22
PDF size: 70.66 Kb.


ABSTRACT

Background: Insulin resistance is defi ned like diminished insulin activity for glucose. The Homeostasis Model Assessment, describesthe grade of insulin resistance in the tissues. With the aging the total body water decreases at intra or extracellular expense. There are in Mexico 9.7 million people between 60 and 80 years old with a prevalence of 23% of diabetes mellitus, 39.3% of overweight, 26.1% of obesity and 55% of arterial hypertension.
Objective: To determine the correlation between the insulin resistance and the total body water in the healthy elderly people.
Material and methods: Observational, transversal, analytic assay. Were included 72 persons older than 60 years of 40 clubs of the old adults in San Luis Potosi city who were sign the informed consent. The studied variables were age, weight, visceral fat, insulinemia, glycaemia, cholesterol, tryglicerids, systolic and diastolic blood pressure, intracellular, extracellular and total body water. We employed central trend measures and dispersion. We used “r” of Pearson analysis for correlation between variables.
Results: 61 (84.1%) were females and 11 (15.3%) males. The average age was 68.3 years. 11.5% of the study people had insulin resistance. The average total body water was 71%. The insulin resistance signifi cantly correlated with the glucose levels (r= 0.429; p= 0.01). The body water content positively correlated with the insulin resistance with signifi cance (p values 0.006). The intracellular water negatively is correlated with the age with p value of 0.021. The average proportion of total body water in elderly people of 60 to 80 years was 45% .
Conclusion: The Mexican elderly persons with insulin resistance have an increase in intracellular, extracellular and total body water; which may be explained by the hyperinsulinemia that produces sodium and water retention.


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