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2004, Number 1

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Cir Cir 2004; 72 (1)

Carcinoma of sebaceous allude of the eyelids

Valenzuela-Flores G, Mozas-Dávila D, Rodríguez-Reyes AA, Gómez-Leal A

Language: Spanish
References: 56
Page: 47-53
PDF size: 83.80 Kb.


ABSTRACT

Sebaceous gland carcinoma is considered a relatively rare tumor and represents approximately 1 and 5% of all eyelid tumors. These tumors usually arise in the Meibomian glands of tarsus, in the Zeis glands, and the sebaceous glands of caruncle or eyebrow. In some instances it had multicentric origin, while in other cases the initial location was unable to be determined. It occurs more frequently in women than in men and presentation age varies from 50 to 90 years. Clinical diagnosis is difficult because is can be confused with chalazion, blepharoconjunctivitis, conjunctivitis, and basocelular carcinoma.
Sebaceous gland carcinoma could go unnoticed; thus, it is necessary to carry out excision of conjunctiva as well as to inform the pathologist of the possibility of malignancy, because pagetoide spread can be easily incorrectly interpreted or not observed even by expert pathologists (up to 50%). Five-years mortality has been estimated at 30% due delayed diagnosis and treatment.
The present work intends to describe incidence, and clinical and histopathologic presentation of sebaceous gland carcinoma during the last 40 years at the Dr. Luis Sanchez Bulnes Hospital, Association to Prevent Blindness in Mexico, as well as to review treatment modalities forecast for this entity.


REFERENCES

  1. Lazcano PE, Hernández AM. Cáncer: frecuencia, factores de riesgo y medidas de prevención. Salud Publica Mex 1997;39:251-252.

  2. Dirección de Estadística, Informática y Evaluación. Estadísticas de mortalidad en México, 1994. México, D.F: Secretaría de Salud;1995.

  3. Parkin M. Global cancer statistics in the year 2000. Lancet Oncol 2001;2:533-542.

  4. Dirección General de Epidemiología. Registro histopatológico de neoplasias malignas/DGE/SSA 2000*. Tasa por 100,000 h. México: Secretaría de Salud.

  5. Kuri MP. Compendio de cáncer, 2000. México: Dirección General de Epidemiología; SSA.

  6. Rodríguez S, Labastida S, Tapia R, Kuri P, Macías C. Registro histopatológico de neoplasias en México. Población derechohabiente del IMSS 1st ed. México: Ciencia y Cultura Latinoamérica; 1999. pp. 18.

  7. Ruíz DF, de Buen S. Tumores palpebrales (estudio de 64 casos). Rev Mex Oftalmol 1987;61:245-247.

  8. Carraway J. The lacrimal system. Plastic Reconstructi Surg 1996;98:1109.

  9. Lee SB, Saw SM, Eong KG, Kah-Guan A, Chan T, Lee HP. Incidence of eyelid in Singapore from 1968 to 1995. Br J Ophthalmol 1999;83: 595-597.

  10. Aurora Al, Blodi FC. Lesions of the eyelids: a clinicopathological study. Surv Ophthalmol 1970;15:94-104.

  11. Kwito Ml, Boniuk M, Zimmerman LE. Eyelid tumors with reference to lesions confused with squamous cell carcinoma: I. Incidence and error in diagnosis. Arch Ophthalmol 1963;69:696-697.

  12. Morgan M, Truitt C, Romer C, Somach S, Pitha J. Ocular adnexa oncocytoma: a case series and clinicopathologic review of the literature. Am J Dermatol 1998;20:487-490.

  13. Harbour JW. Tumors of the eye and ocular adnexa. 1st ed. B.C. Decker, Inc; 2001. pp. 1-23.

  14. Kass LG, Hornblass A. Sebaceous carcinoma of the ocular adnexa. Surv Ophthalmol 1989;33:477-490.

  15. Karamursel E, Polcharoen W, Chan R, Foster S. Ocular surface neoplasia masquerading as chronic blepharoconjunctivitis. Cornea 1999; 18:282-288.

  16. Schlernitzauer D, Font R. Sebaceous gland carcinoma of the eyelid. Arch Ophthalmol 1976;94:1523-1525.

  17. Rumelt S, Hogan N, Rubin P, Jakohtec F. Four-eyelid sebaceous cell carcinoma following irradiation. Arch Ophthalmol 1998;116:1670-1672.

  18. Tesluk G. Eyelid lesions: incidence and comparison of benign and malignant lesions. Ann Ophthalmol 1985;17:704-707.

  19. Sihota R, Tandon K, Vetaria SM. Malignant eyelid tumors in an Indian population. Arch Ophthalmol 1996;114:108-109.

  20. Taylor R, Lehman J. Sebaceous adenocarcinoma of the Meibomian gland. Arch Ophtalmol 1969;82:66-68.

  21. Best M, Chabon A, Park J, Galin M. Sebaceous carcinoma of glands of Zeis. New Y S J Med 1970:433-435.

  22. Wolfe JT, Yeats RP, Wick MR. Sebaceous carcinoma of the eyelid. Am J Surg Pathol 1984;8:597-506.

  23. Gloor P, Ansari I, Sinard J. Sebaceous carcinoma presenting as a unilateral papillary conjunctivitis. Am J Ophthalmol 1999;127:458-459.

  24. Rao NA, Hidayat AA, Mc Lean I, Zimmerman LE. Sebaceous carcinomas of the ocular adnexa: a clinicopathologic study of 104 cases, with five year follow-up data. Hum Pathol 1982;13:113-122.

  25. Margo C, Grossniklaus H. Intraepithelial sebaceous neoplasia without underlying invasive carcinoma. Surg Ophthalmol 1995;39:293-301.

  26. Robson A, Millard P, Hollowood K. Extra ocular sebaceous carcinoma in situ. A case report. Br Assoc Dermatol 1998;139:85.

  27. Ginsberg J. Present status of Meibomian gland carcinoma. Arch Ophthalmol 1965;73:271-277.

  28. Omura N, Collison D, Perry A, Myers L. Sebaceous carcinoma in children. J Am Acad Dermatol 2002;47:950-953.

  29. Zurcher M, Hinstschich A, Bunce C, Collin JR. Sebaceous carcinoma of the eyelid a clinicopathological study. Br J Ophthalmol 1998; 82:1049-1055.

  30. Chao AN, Shields C, Krema H, Shields J. Outcome of patients with periocular sebaceous gland carcinoma with and without conjunctival intraepitelial invasion. Ophthalmology 2001;108:1833-1877.

  31. Bauninger G, Hood I, Worthen D, Gainsesville F. Sebaceous carcinoma of lid margin masquerading as cutaneous horn. Arch Ophthalmol 1973;90:380-381.

  32. Luthra C, Doxanas M, Green R. Lesions of the caruncle: a clinicohistopathologic study. Surv Ophthalmol 1978;23:183-195.

  33. Doxanas M, Green R. Sebaceous gland carcinoma. Review of 40 cases. Arch Opthalmol 1984;102:245-250.

  34. Condon G, Brownstein S, Codere F. Sebaceous carcinoma of the eyelid masquerading as superior limbic keratoconjunctivitis. Arch Ophthalmol 1985;103:1525-1529.

  35. Brownstein S, Codere F, Jackson B. Masquerade syndrome. Ophthalmology 1980;87:259-262.

  36. Foster S, Allasmith M. Chronic unilateral blepharoconjunctivitis caused by sebaceous carcinoma. Am J Ophthalmol 1978;86:218-220.

  37. Reese A. Tumors of eye. 3rd ed. Harper & Row Publishers; Inc.;1976.pp. 37-62.

  38. Ricahardson EC. An unusual presentation of primary sebaceous carcinoma of the conjunctiva. Eye 1998;12(II):325-327.

  39. Gómez AF, Reséndiz CJ, Rodríguez CAS. Cáncer de piel. Tumores de cabeza y cuello. 2ª edición. México: El Manual Moderno; 2003. pp. 267-309.

  40. Folberg R, Salomao D, Grossniklaus H, Proia A, Rao N, Cameron JD. Recommendations for the reporting of tissues removed as part of the surgical treatment of common malignancies of the eye and its adnexa. Am J Surg Pathol 2003;27:999-1004.

  41. Misago N, Mihara I, Ansai S, Narisawa Y. Sebaceous and related neoplasms with sebaceous differentiation. Am J Dermatopathol 2002; 24:294-304.

  42. Nunery W, Welsh M. Recurrence of sebaceous carcinoma of the eyelid after radiation therapy. Am J Ophthalmol 1983;96:10-15.

  43. Moreno C, Jacyk W, Judd M, Requena L. Highly aggressive extraocular sebaceous carcinoma. Am J Dermatopathol 2001;23:450-455.

  44. Gutiérrez M, González F, Gutiérrez E, Suárez E, San Martín J, Gómez I. Epiteliomas espinocelulares palpebrales: 18 casos. Arch Esp Oftalmol 2000;10:1-5.

  45. Taylor R, Lehman J. Sebaceous adenocarcinoma of the Meibomian gland. Arch Ophthalmol 1969;82:66-68.

  46. Dennis L, Ka T, Fan D, Wah C. An uncommon malignant neoplasm of the caruncle; report of a case of undifferentiated carcinoma. Arch Ophthalmol 1998;116:374-376.

  47. González F, Kaltreider S, Patnaik BD, Retief J, Bao Y, Newman S, Stoler M, Levine P. Sebaceous carcinoma. Ophthalmology 1998; 105:497-506.

  48. Chong AH, Gibbs S, Todd P, Grant JW. The significance of solitary sebaceous neoplasms. Br Assoc Dermatol 2000;143:96.

  49. Shwartz RA, Torre DP. The Muir Torre syndrome: a 25 year retrospect. J Am Acad Dermatol 1995;33:90-104.

  50. Harwood C, Swale V, Bataille V, Quinn A, Cerio R, McGregor J. Sebaceous carcinoma and microsatellite instability in immunosuppressed organ transplant recipients. Br Assoc Dermatol 2000;142:610.

  51. Lucas DR. Greer´s ocular pathology. 4th Ed. Blackwell Science Publications; 1989. pp. 81-99.

  52. Levine P, Dutton J. A 20 year series of orbital exenteration. Am J Ophthalmol 1991;112:496-501.

  53. Shields C, Naseripour M, Shields J, Eagle R. Topical mytomicin-C for pagetoid invasion of the conjunctiva by eyelid sebaceous gland carcinoma. Ophthalmology 2002;109:2129-2133.

  54. Lisman R, Jakobiec F, Small P. Sebaceous carcinoma of the eyelids. The role of adjunctive cryotherapy in the management of conjunctival pagetoid spread. Ophthalmology 1989;96:1021-1026.

  55. Spencer J, Nossa RM, Tse D, Sequeira M. Sebaceous carcinoma of the eyelid treated with Mohs micrographic surgery. J Am Acad Dermatol 2001;44:1004-1009.

  56. Gardetto A, Rainer C, Ensinger C, Baldisera I, Piza Katzer H. Sebaceous carcinoma of the eyelid: a rarity worth considering. Br J Ophthalmol 2002;86:243-244.




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