2010, Number 1
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Rev Endocrinol Nutr 2010; 18 (1)
Thyroid cancer: A case series from Centro Médico Nacional «20 de Noviembre»
Flores-Ortega A, Rivera-López E, Guillén-González MA, Vergara-López A
Language: Spanish
References: 22
Page: 11-17
PDF size: 199.37 Kb.
ABSTRACT
Background: A timely diagnosis and the availability of an adequate management paradigm, along with a relatively benign biological behavior, make of well differentiated thyroid cancer (WTC) a neoplasm with a good prognosis. The present report describes the experience with this tumor at our Institution.
Material and methods: It is a descriptive, cross-sectional and observational study. We reviewed the medical records of patients with the diagnosis of thyroid cancer between January 2000 and December 2008. The following variables were analyzed: gender, age at diagnosis, presenting complaint, time between onset of symptom and diagnosis, histopathological diagnosis, TNM stage, treatment, recurrences, thyroglobulin level, and activity/death at the time of the study.
Results: 263 medical records of patients with WTC were reviewed; there was a female predominance with a ratio of 11:1; the average age at diagnosis was 42 years, the time between the initial complaint and diagnosis was, on average 1 year. Papillary cancer was present in 90.1% of patients and follicular in 9.9%. Ninety seven patients (35%) showed recurrence. Recurrence was associated with age at diagnosis from 20 to 29 years, an inappropriate initial surgical approach and an inadequate ablative therapy.
Conclusions: Our results are comparable with those of other studies. Coincidences were found in age at diagnosis, histology, and ablative therapy. In our center, we apply the American Thyroid Association Guidelines.
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