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2010, Number 1

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Ortho-tips 2010; 6 (1)

Aspectos básicos del remodelamiento óseo y su aplicación clínica

Gómez GF
Full text How to cite this article

Language: Spanish
References: 6
Page: 39-49
PDF size: 159.06 Kb.


Key words:

Bone tissue properties, remodeling, turnover, bone resorption, osteoblast, osteocyte, osteoclast, biochemical turnover markers, bone densitometry.

ABSTRACT

Bone tissue properties are: grow, modeling and remodeling or turnover. The first two properties occur during the first three decades of life; however, the last one is carried during whole life. These properties are due to the cellular bone activity: the osteblasts are the bone forming cells, the osteocytes maintain their structure and the osteoclasts are responsableof bone resorption. The activity of these cells is determined by systemic mediators as parathyroid hormone, sex hormones and vitamin D and also by important local mediators. The balance between these properties determine bone health, but this balance can be altered by lifestyle, nutrition, systemic conditions and other factors. The level of activity of these processes can be monitored through a bone densitometry, metabolites titration and histopathological study.


REFERENCES

  1. Gómez-García F, Vázquez-Martínez JL, Lara-Rodríguez MA. Osteoporosis y osteopenia en mujeres trabajadoras de la salud en la ciudad de México. Acta Ortop Mex 2008; 22(5): 292-302.

  2. Bonnick SL MD, FACP. Bone Densitometry in Clinical Practice: Application and Interpretation. Third Edition. Humana Press, 2010.

  3. Meier Ch, Seibel MJ, Kraenzlin ME. Biochemical Merkers of Bone Turnover–Clinical Aspects. From: Contemporary Endocrinology: Osteoporosis: Pathophysiology and Clinical Management Ed. R.A. Adler. Humana Press. 2010: 131-156.

  4. Seibel MJ, Meier Ch. Biochemical Markers of Bone Turnover – Basic Biochemistry and variability. From: Contemporary Endocrinology: Osteoporosis: Pathophysiology and Clinical Management Edited By: R.A. Adler. Humana Press. 2010: 97-130.

  5. Merz WA, Schenk RK. Quantitative structural analysis of human cancellous bone. Acta Anat (Basel) 1970; 75(1): 54-66.

  6. Merz WA, Schenk RK. A quantitative histological study on bone formation in human cancellous bone. Acta Anat (Basel) 1070; 76(1): 1-15.




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C?MO CITAR (Vancouver)

Ortho-tips. 2010;6