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2010, Number 1

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Ortho-tips 2010; 6 (1)

Padecimientos sistémicos que afectan el metabolismo óseo

Preciado SA

Language: Spanish
References: 27
Page: 31-38
PDF size: 92.86 Kb.


ABSTRACT

The main functions of the skeleton are body support and organ protection. In addition, it contributes with important metabolic process like hematopoiesis and calcium and phosphorus reservoirs. Three functions are carried out during life time: calcification, rest and bone resorption. For about the 40 first years of age bone mass is gained, but after this age, bone resorption prevail over the other functions and further fractures risk increases. There are external factors or pathogenic states that can hinder the formation of an optimal bone mass or accelerate her resorption. The age by itself, is a factor that gradually triggers this process. However, diseases like diabetes, kidney disorders and malignant tumors among others, could increase the consumption of bone mass. Also therapies such as use of corticosteroids, immunosuppressive drugs administration and some lifestyles as sedentarism, alcoholism and others can increase this process and produce premature and severe osteoporosis.


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