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2010, Number 1

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Rev Med Hosp Gen Mex 2010; 73 (1)

Survival and prognostic factors in esophageal cancer

Cruz-Zárate A, Hernández-Guerrero A, Sobrino-Cossio S, Barranco-Fragoso B, Alonso-Lárraga JO

Language: Spanish
References: 16
Page: 23-29
PDF size: 114.23 Kb.


ABSTRACT

Introduction: Esophageal cancer worldwide is 8th in frequency and has poor survival (20%). It is the 6th cause of cancer related deaths. In the last years there have been epidemiologic changes with an increase in the frequency of adenocarcinoma. Prognostic factors besides are clinical stage, advanced age, dysphagia, weight loss, tumor size and micrometastasis. Objective, to describe the clinical characteristics, prognostic factors and survival esophageal cancer. Methods: Retrospective, longitudinal, analytic study of esophageal cancer patients at the Instituto Nacional de Cancerologia in Mexico City from 2005 to 2008. Results: 142 patients. The frequency of both histological types was similar. It was more frequent among men. There was no statistically significant difference for age, dysphagia, platelet count or albumin. There was a higher frequency of obesity and overweight in patients with adenocarcinoma. At the time of diagnosis, patients with squamous cell carcinoma were at a more advanced stage. There were no statistically significant differences in overall survival. Conclusions: In our study, the relation in two subtypes of esophageal cancer was 1:1, with both being more frequent in men. Overweight and obesity were more predominant in patients with adenocarcinoma, while patients with squamous cell carcinoma presented at a more advanced stage. There was no difference in overall survival between groups.


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