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ISSN 2448-8909 (Print)

2010, Number 2

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Med Crit 2010; 24 (2)

Clinical benefits of continuous renal replacement therapy in critically ill patients with acute renal failure

Canseco MJE, Luviano GJA, Macías GMT

Language: Spanish
References: 21
Page: 66-71
PDF size: 51.06 Kb.


ABSTRACT

Introduction: Renal replacement therapy (RRT) for acute renal failure (ARF) can be applied intermittently (IRRT) or continuously (CRRT).
Objective: To determine the behavior of renal function and hemodynamic during continuous renal replacement therapy (CRRT).
Design: Prospective, experimental time series of a group.
Setting: Intensive Care of tertiary in Monterrey, NL. México.
Patients: With ARF from 18-80 years old in stage I (injury) or F (failed) RIFLE criteria and patients with chronic kidney disease (CKD).
Interventions: Mahurker catheter through connection system prisma haemodiafiltration mode venovenous continuous effluent 35 mL/kg (Ronco), extraction rate under the water balance, dializant liquid/liquid reinjection of 70:30, minimum 72 hours of treatment. Hemodynamic dates were recorded and renal functions test.
Results: We analyzed 24 patients, age 45.8 years old (22-77), 2 in stage I (8.8%), 17 in stage F (60.2%), and 5 in CKD (21%), APACHE II 23.4 ((± 3.1). By Friedman test significant difference from the first 24 hours for urea, creatinine, pH, bicarbonate, heart rate and blood pressure. Mortality was 70.8%.
Conclusions: CRRT normalized urea, creatinine, bicarbonate, maintaining acid-base balance and hemodynamic stability from the first 8 hours of treatment.


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