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2009, Number 4

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Rev Endocrinol Nutr 2009; 17 (4)

Glutamine in clinical nutrition

Canul-Medina G, Coop-Gamas O, Guevara-Guarfias U, Montaño-Candia MT, Machado-Villarroel L, Montaño-Candia M, Zúñiga-Rivera A

Language: Spanish
References: 87
Page: 161-169
PDF size: 173.11 Kb.


ABSTRACT

The supplementation of glutamine (Gln) has been effective to reduce the morbi-mortality of the catabolic patient and to protect against phenomena of oxidative stress. Gln is an essential amino acid involved in the synthesis of urea in liver, ammonia in the kidney, as well as glycogenesis and serves as a source of energy for some cells. Under stressful conditions its concentration falls and it needs to be supplemented in order to avoid systemic complications. It is a precursor of glutathione and of the neurotransmitter glutamate and is also considered a powerful antioxidant. Its supplementation is recommended in patients with serious illnesses, particularly those in Intensive Care suffering from hemato-oncological conditions and extensive burns, among others. The purpose of this revision is to summarize the most important applications of glutamine in clinical nutrition


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