Barnes AI, Arce MJE, Cosiansi MC, Farías A, Paraje MG

Language: English
References: 21
Page: 72-78
PDF size: 475.26 Kb.

ABSTRACT

The objective of this paper was to evaluate the bacterial resistance to antibiotics in inpatients as well as in outpatients who have been diagnosed as having urinary tract infections (UTI), by analyzing the resistance profiles to different antibiotics related to E. coli and Staphylococcus sp. In this way, epidemiologic data was also added to the empirical prescription. We conducted our study on patients with UTI who attended a Public Health Care Center in Argentina. Data were collected by retrospective observational research from 2,800 adults, over a three-year period. Positive diagnoses were analyzed according to gender, and differences between outpatients and inpatients. The resistance of E. coli to nitrofurantoine (NIT) and gentamicin (GEN) in female outpatients was of 6 and 5% respectively, with these figures rising to 13 and 27% in inpatients. The resistance to trimethoprime-sulfamethoxazol (TMS) and norfloxacin (NOR) was higer in inpatients. The global resistance of E. coli and Staphylococcus sp. to NOR was approximately 55%, and the resistance to ampicillin (AMP) was greater than 70% in inpatients. Few previous studies have been undertaken in Argentina similar nature to this one. Therefore, the selection and prescription of an antimicrobial needs be evaluated in future with more complex parameters in order to obtain more accurate analysis of regional epidemiologic data, thus enabling better empirical therapies.

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