Santillana EE, Ávila EF

Language: Spanish
References: 24
Page: 118-129
PDF size: 65.81 Kb.

ABSTRACT

Introduction: The prevalence of insulin resistance (IR) in patients with infertility is 50 to 60%. The severity of both increases with obesity and 75% of obese patients suffering from RI. Objective: To identify the frequency of IR in patients with infertility at the Hospital of Gynecology and Obstetrics IMIEM, served in the Department of Biology of Human Reproduction 1 August 2007 to July 31, 2008. Methods: Retrospective, observational, transverse and descriptive. We reviewed all cases of infertility by definition presenting RI. The RI was diagnosed by clinical data and the quantitative index of insulin sensitivity (QUICKI) and homeostasis model of assessment (HOMA). We assessed body mass index, serum androgen and progesterone. We measure of central tendency. Results: 216 patients attended the consultation, 82 patients were asked to test serum insulin, resulting in 39 (18%) with RI, mean age 28 years. Primary infertility presented 24 (61.5%) and secondary 15 (38.5%), overweight or obesity in 31 (71%), clinical data of hyperandrogenism 21 (53.8%). The 39 patients were managed with metformin and weight loss. Pregnancy was achieved in 18 (46.1%) patients, 3 (16.6%) were resolved in spontaneous abortions, 1 (5.5%) in immature birth, 6 (33.3%) and cesarean section 8 (38.8%) in labor with eutopic pregnancy term. Conclusions: The RI was submitted in 18% of our patients with infertility, lower than reported. Pregnancy was achieved in 46%.

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