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Boletín Médico del Hospital Infantil de México

2010, Number 2

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Bol Med Hosp Infant Mex 2010; 67 (2)

Solid pseudopapillary tumor of the pancreas in pediatric patients. Case report and literature review

Camacho AJF, Duarte VJC, Hidalgo CJF, Valenzuela EA, Ortíz EP

Language: Spanish
References: 51
Page: 133-141
PDF size: 214.93 Kb.


ABSTRACT

Background: Solid pseudopapillary tumor (SPT) of the pancreas is a low-grade epithelial malignant tumor principally affecting young women and represents ~1-2% of all pancreatic neoplasms. We present a case of this type of tumor treated at the General Hospital of Tijuana in the service of pediatric surgery. We also present a review of the literature.
Case: We present the case of a 12-year-old female with symptomatology of a progressively growing palpable tumor in the upper abdomen. She was diagnosed with SPT located in the tail of the pancreas. It was treated successfully with distal pancreatectomy without splenectomy. The patient was discharged on the third postsurgical day.
Discussion: SPT is a differential diagnosis with the presence of a mass at the level of the pancreas. Due to its rarity, it is not the first option to rule out, especially in pediatric patients. Surgery alone represents the best treatment for this pathological entity and should be attempted in all cases, independent of the size of the pancreatic lesion.


REFERENCES

  1. Kato T, Egawa N, Kamisawa T, Tu Y, Sanaka M, Sakaki N, et al. A case of solid pseudopapillary neoplasm of the pancreas and tumor doubling time. Pancreatology 2002;2:495-498.

  2. Martin RCG, Klimstra DS, Brennan MF, Conlon KC. Solid-pseudopapillary tumor of the pancreas: a surgical enigma? Ann Surg Oncol 2002;9:35-40.

  3. Ulusan S, Bal N, Kizilkilic O, Bolat F, Yildirim S, Yildirim T, et al. Solid-pseudopapillary tumour of the pancreas associated with dorsal agenesis. Br J Radiol 2005;78: 441-443.

  4. Jiménez MFJ, Tolosa I, De Blas A, García SJ, Cabada T, Olier J. Tumores quísticos pancreáticos y lesiones pseudotumorales. An Sis Sanit Navar 2003;26:243-250.

  5. De Castro SMM, Singhal D, Aronson DC, Busch ORC, van Gulik TM, Obertop H, et al. Management of solid-pseudopapillary neoplasms of the pancreas: a comparison with standard pancreatic neoplasm. World J Surg 2007;31:1129-1134.

  6. Iribarren DM, Castro PG, Fernández MR, Meléndez VR, Freiria BG, García LF, et al. Neoplasia epitelial pseudopapilar sólido-quística de páncreas (tumor de Frantz). Estudio de dos nuevos casos. Rev Esp Enferm Dig 2004;96:877-878.

  7. Costa-Neto GD, Amico EC, Costa GID. Tumor sólido-cístico pseudopapilar do páncreas (tumor de Frantz). Estudo de quatro casos. Arq Gastroenterol 2004;41:259-262.

  8. Targarona J, Paggi L, Garatea R, Romero C, Rosamedina JL, Lora A, et al. Tumores sólidos pseudopapilares de páncreas. Reporte de 7 casos y revisión de la literatura. Rev Gastroenterol Perú 2007;27:185-190.

  9. Valdés R, Molinar L, Ortega J. Neoplasia epitelial papilar sólida y quística de páncreas. Imágenes del tumor y seguimiento. Gac Med Mex 1999;135:333-337.

  10. Cervantes MF, Florez ZC, Álvarez MI. Tumor pseudopapilar sólido-quístico de páncreas. Presentación aguda postraumática. Reporte de un caso y revisión de la literatura. Rev Gastroenterol Mex 2002;67:93-96.

  11. González M, Aldrete J. Neoplasias quísticas del páncreas: informe de tres casos de difícil diagnóstico. Rev Inv Clin 1995;47:43-48.

  12. Rebhandl W, Felberbauer FX, Puig S, Paya K, Hochschorner S, Barlan M, et al. Solid-pseudopapillary tumor of the pancreas (Frantz tumor) in children: report of four cases and review of the literature. J Surg Oncol 2001;76:289-296.

  13. Abraham SC, Klimstra DS, Wilentz RE, Yeo CJ, Conlon K, Brennan M, et al. Solid-pseudopapillary tumors of the pancreas are genetically distinct from pancreatic ductal adenocarcinomas and almost always harbor â-catenin mutations. Am J Pathol 2002;160:1361-1369.

  14. Frago R, Fabregat J, Jorba R, García BF, Altet J, Serrano MT, et al. Tumor sólido pseudopapilar de páncreas: diagnóstico y tratamiento curativo. Rev Esp Enferm Dig 2006;98:813-816.

  15. Hyang ES, Myung KL, Young DL, Seong WJ, Chang MC, Won YT, et al. Solid pseudopapillary tumor of the pancreas. J Clin Gastroenterol 2006;40:919-922.

  16. Coleman KM, Doherty MC, Bigler SA. Solid-pseudopapillary tumor of the pancreas. Radiographics 2003;23: 1644-1648.

  17. Karagülle E, Yildirim E, Kiyici H, Karakayali H. Solid pseudopapillary of the pancreas: a case report. Turk J Gastroenterol 2006;17:316-319.

  18. Salla C, Chatzipantelis P, Konstantinou P, Karoumpalis I, Pantazopoulou A, Dappola V. Endoscopic ultrasound-guided fine-needle aspiration cytology diagnosis of solid pseudopapillary tumor of the pancreas: a case report and literature review. World J Gastroenterol 2007;13:5158-5163.

  19. Jin YC, Myeong JK, Joo HK, Seung HK, Joon Sl, Young TO, et al. Solid pseudopapillary tumor of the pancreas: typical and atypical manifestations. Am J Radiol 2006;187:W178-W186.

  20. Choi SH, Kim SM, Oh JT, Park JY, Seo JM, Lee SK. Solid pseudopapillary tumor of the pancreas: a multicenter study of 23 pediatric cases. J Pediatr Surg 2006;41: 1992-1995.

  21. Machado MCC, Machado MAC, Bacchella T, Jukemura J, Almeida JL, Cunha JEM. Solid pseudopapillary neoplasm of the pancreas: distinct patterns of onset, diagnosis, and prognosis for male versus female patients Surgery. 2008;143:29-34.

  22. Geers C, Moulin P, Gigot JF, Weynand B, Deprez P, Rahier J, et al. Solid and pseudopapillary tumor of the pancreas-review and new insights into pathogenesis. Am J Surg Pathol 2006;30:1243-1249.

  23. Fernández JA. Tumores quísticos del páncreas: revisión de la literatura. Cir Esp 2003;73:297-298.

  24. Salvia R, Bassi C, Festa L, Falconi M, Crippa S, Butturini G, et al. Clinical and biological behavior of pancreatic solid pseudopapillary tumors: report on 31 consecutive patients. J Surg Oncol 2007;95:304–310.

  25. Adams AL, Siegal GP, Jhala NC. Solid pseudopapillary tumor of the pancreas. A review of salient clinical and pathological features. Adv Anat Pathol 2008;15:39-45.

  26. Notohara K, Hamazaki S, Tsukayama C, Nakamoto S, Kawabata K, Mizobuchi K, et al. Solid-pseudopapillary tumor of the pancreas. Immunohistochemical localization of neuroendocrine markers and CD10. Am J Surg Pathol 2000; 4:1361-1371.

  27. El-Bahrawy MA, Rowan A, Horncastle D, Tomlinson I, Theis BA, Russell RCG, et al. E-cadherin/catenin complex status in solid pseudopapillary tumor of the pancreas. Am J Surg Pathol 2008;32:1-7.

  28. Yeh TS, Jan YY, Chiu CT, Ho YB, Chen TC, Lee KF, et al. Characterisation of oestrogen receptor, progesterone receptor, trefoil factor 1, and epidermal growth factor and its receptor in pancreatic cystic neoplasms and pancreatic ductal adenocarcinoma. Gut 2002;51: 712-716.

  29. Tanaka Y, Kato K, Notohara K, Hojo H, Ijiri R, Miyake T, et al. Frequent b-catenin mutation and cytoplasmic/nuclear accumulation in pancreatic solid-pesudopapillary neoplasm. Cancer Res 2001;61:8401-8404.

  30. Tang LH, Aydin H, Brennan MF, Klimstra DS. Clinically aggressive solid pseudopapillary tumors of the pancreas. A report of two cases with components of undifferentiated carcinoma and comparative clinicopathologic analysis of 4 conventional cases. Am J Surg Pathol 2005;29:512-519.

  31. Nakagohri T, Kinoshita T, Konishi M, Takahashi S, Gotohda N. Surgical outcome of solid pseudopapillary tumor of the pancreas. J Hepatobiliary Pancreat Surg 2008;15:318-321.

  32. Patil TB, Shrikhande SV, Kanhere HA, Saoji RR, Ramadwar MR, Shukla PJ. Solid pseudopapillary neoplasm of the pancreas: a single institution experience of 14 cases. HPB 2006;8:148-150.

  33. Sheehan MK, Beck K, Pickleman J, Aranha GV. Spectrum of cystic neoplasms of the pancreas and their surgical management. Arch Surg 2003;138:657-662.

  34. Kasem A, Ali Z, Ellul J. Papillary cystic and solid tumour of the pancreas: report of a case and literature review. World J Surg Oncol 2005;3:62.

  35. Cantisani V, Mortele KJ, Levy A, Glickman JN, Ricci P, Passariello R, et al. MR imaging features of solid pseudopapillary tumor of the pancreas in adult and pediatric patients. Am J Roentgenol 2003;181:395-401.

  36. Salvia R, Festa L, Butturini G, Tonsi A, Sartori N, Biasutti C, et al. Pancreatic cystic tumors. Minerva Chir 2004;59:185-207.

  37. Hernández PA, Artigas V, Moral AM, Magarzo J, Targarona E, Trias MS. Tumor sólido pseudopapilar del páncreas. Cir Esp 2005;77:233-235.

  38. Zinner MJ. Solid and papillary neoplasms of the pancreas. Surg Clin North Am 1995;75:1017-1024.

  39. Rutland B, Pollock J, Thompson L, Tucker JA, Boudeaux C. Solid-pseudopapillary tumor: a report of three cases in adult males diagnosed utilizing three different modalities. Diagn Cytopathol 2007;35:234-238.

  40. Choi EK, Ho PS, Yoon KD, Won KK, Ho BJ, Gyu LM, et al. Unusual manifestations of primary pancreatic neoplasia: radiologic-pathologic correlation. J Comput Assist Tomogr 2006;30:610-617.

  41. Nakatani K, Watanabe Y, Okumura A, Nakanishi T, Nagayama M, Amoh Y, et al. MR imaging features of solid-pseudopapillary tumor of the pancreas. Magn Reson Med Sci 2007;6:121-126.

  42. Voss M, Hammel P, Molas G, Dancour A, O’Toole D, Terris B, et al. Value of endoscopic ultrasound guided fine needle aspiration biopsy in the diagnosis of solid pancreatic masses. Gut 2000;46:244-249.

  43. Nadler EP, Novikov A, Landzberg BR, Pochapin MB, Centeno B, Fahey TJ, et al. The use of endoscopic ultrasound in the diagnosis of solid pseudopapillary tumors of the pancreas in children. J Pediatr Surg 2002;37: 1370-1373.

  44. Lee JK, Tyan YS. Detection of a solid pseudopapillary tumor of the pancreas with F-18 FDG positron emission tomography. Clin Nucl Med 2005;30:187-188.

  45. Hah JO, Park WK, Lee NH, Choi JH. Preoperative chemotherapy and intraoperative radiofrequency ablation for unresectable solid pseudopapillay tumor of the pancreas. J Pediatr Hematol Oncol 2007;29:851-853.

  46. Sperti C, Berselli M, Pasquali C, Pastorelli D, Pedrazzoli S. Aggressive behavior of solid-pseudopapillary tumor of the pancreas in adults: a case report and review of the literature. World J Gastroenterol 2008;14:960-965.

  47. Albores SJ, Simpson KW, Bilello SJ. The clear cell variant of solid pseudopapillary tumor of the pancreas: a previously unrecognized pancreatic neoplasm. Am J Surg Pathol 2006;30:1237-1242.

  48. Koukoutsis I, Tamijmarane A, Bellagamba R, Bramhall S, Buckels J, Mirza D. The impact of splenectomy on outcomes after distal and total pancreatectomy. World J Surg Oncol 2007;5:61.

  49. Tornóczky T, Kálmán E, Jáksó P, Pajor L, Kajtár GG, Davidovics S, et al. Solid and papillary epithelial neoplasm arising in heterotopic pancreatic tissue of the mesocolon. J Clin Pathol 2001;54:241-246.

  50. Shao QC, Sheng QZ, Qi BD, Hong L. Clinical analysis of solid-pseudopapillary tumor of the pancreas: report of 15 cases. Hepatobiliary Pancreat Dis Int 2008;7:196-200.

  51. Vollmer CM, Dixon W, Grant DR. Management of a solid pseudopapillary tumor of the pancreas with liver metastases. HPB 2003;5:264-267.




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