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2009, Number 3

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Rev Inst Nal Enf Resp Mex 2009; 22 (3)

Recent advances in the physiopathological knowledge of idiopathic pulmonary fibrosis

Vega MA, Ruiz LVM

Language: Spanish
References: 55
Page: 190-197
PDF size: 82.79 Kb.


ABSTRACT

The understanding of molecular mechanisms involved in idiopathic pulmonary fibrosis (IPF) has undergone a great expansion during the last decade. The application of diverse classic methodologies of biochemistry, molecular biology and genetics has been crucial to understand IPF physiopathology, and an example of this is the discovery of the roles of telomerase and fibroblasts recruitment in the development of the disease. In contrast, microarray and proteomic technologies have yet a very limited elucidation power. In the future, we could be witnesses of significant advances in the way data is analyzed through these technologies, in order to understand the mechanisms, treatments and eventual processes of this disease.


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