medigraphic.com
ISSN 1405-1699 (Print)
Órgano Oficial del Colegio Mexicano de Alergia, Asma e Inmunología Pediátrica y de la Asociación Latinoamericana de Pediatría

2002, Number 2

<< Back Next >>

Alerg Asma Inmunol Pediatr 2002; 11 (2)

Clinical manifestations of Behçet´s disease in pediatric patients. Experience at Pediatrics National Institute

Chávez GLE, Penagos PM, Yamazaki MA, Berrón PR

Language: Spanish
References: 7
Page: 38-40
PDF size: 71.62 Kb.


ABSTRACT

Behçet´s disease is a systemic vasculitis usually involves eyes, skin, joints, the oral cavity, blood vessels and central nervous system. Infectious agents, immune mechanisms and genetic factors are implicated in the etiopathogenesis of the disease, which remains to be elucidated. The aims of this study was to describe the clinical manifestations of the Behçet´s disease in pediatric patients of the “Instituto Nacional de Pediatría”. We realized retrolectivo study, comparative and cross-sectional. We revised medical records of the children with Behcet´s disease since January 1988 to December 2001. All patients presented oral ulcerations, 6 patients with genital ulcerations, but none patient presented eye lesions. Others manifestations were: skin manifestations in 9 patients, fever in 8, arthritis in 4, ulcerative colitis in 1 and one patient was central nervous system involvement. With talidomida use, to return of the ulcers was minor and less frequently. Four patients treated with talidomida for two years no presented return of the ulcers.


REFERENCES

  1. Kaklamani VG, Evaiopoulous G, Kaklamanis PG. Behçet’s disease. Sem Arth Rhem 1998; 27: 197-217.

  2. Behçet’s disease Research Committee of Japan. Behcet’s disease: Guide to diagnosis of Behçet´s disease. Jap J Ophthalmol 1974; 18: 291-4.

  3. Messini H, Spyropoulus M, Papadimitroupoulous M, Koumantaki Y, Giziaki E, Stavroupoulus C et al. HLA-B5 (51) genomic analysis in Greek patients with adamanties-Behçet’s disease. Correlation with certain disease characteristics. In 7th International Conference of Behçet’s Disease (Abstract A 34). Revue du Rheumat 1996; 63: 534.

  4. Mizuki N, Ohno SH. Immunogenetic studies of Behcet’s disease. In 7th International Conference of Behçet’s Disease (Abstract A 34). Rev Rheumat 1996; 63: 520-7.

  5. Pande L, Uppal SS, Kailash S, Kumar A, Maloviya AN. Behçet’s disease in India: a clinical immunological, immunogenetic and outcome study. Br Rheumatol 1995; 34-825-30.

  6. Hamza M Foreword In: In 7th International Conference of Behçet’s Disease Tunis, Tunisa, October 10-11, 1996. Revue Rheum 1996; 63: 508.

  7. Kaklamani VG, Evaiopoulous G, Kaklamanis PG. Behçet’s disease. Sem Arth Rhem 2001; 17: 107-17.




2020     |     www.medigraphic.com