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2009, Number 4

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Acta Med 2009; 7 (4)

Septic shock in a patient with parvovirus B-19 - Etiological agent or opportunistic infection?

Rojo EA, Orzechowski RA, Videgaray OF

Language: Spanish
References: 35
Page: 205-209
PDF size: 196.29 Kb.


ABSTRACT

The human parvovirus B19 is a DNA virus, causative agent of the childhood disease known as erythema infectiosum. In adults is a disease self-limited, with fever, arthralgia, rash, fatigue and edema. In immunocompromised patients can cause chronic anemia. Have been reported isolated cases of serious infections such as parvovirus B19 myocarditis, vasculitis, lymphadenitis, autoimmune thrombocytopenic purpura, hemophagocytic syndrome, fulminant hepatitis, pericarditis, pneumonia, aplastic anemia, acute renal failure, seizures and one case of severe sepsis. Antibody detection is the usual system for diagnosis of recent infection, it can also demonstrate the presence of the virus by electron microscopy, antigen detection and DNA detection of the virus. Treatment is symptomatic with nonsteroidal anti-inflammatory. Treatment of persistent infection in immunosuppressed patients is with intravenous immunoglobulin. We report the case of a healthy adult with parvovirus B19 infection that infiltrates and presented in the following 12 hours evolved to septic shock. We performed a comprehensive study to find the causative agent and only positive serology and PCR for parvovirus B19 was found.


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