2009, Number 2
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Rev Inst Nal Enf Resp Mex 2009; 22 (2)
CIinical description of cystic fibrosis patients at the National Institute of Respiratory Diseases, 1995-2008
Vázquez AKJ, Alejandre GA, García SFMC
Language: Spanish
References: 16
Page: 84-91
PDF size: 79.67 Kb.
ABSTRACT
Background and objective: The incidence of cystic fibrosis (CF) in Mexican population is 1/8,500 live births, and the life expectancy of these patients is 9 years. The objective of this study was to describe the clinical characteristics of children diagnosed with CF who attended the National Institute of Respiratory Diseases Ismael Cosío Villegas (INER) between 1995 and 2008.
Methods: Clinical charts of CF patients diagnosed through iontophoresis and who were seen at the INER during a 13-year period were retrospectively reviewed. Information on sociodemographic characteristics, time intervals between onset of symptoms, diagnosis and death, laboratory test results (hemoglobin, serum albumin, triglycerides and cholesterol), clinical pattern, and complications associated with CF were recorded. Results concerning arterial blood gases and spirometry were also obtained. All data were referred to the time of admission to the INER.
Results: A total of 35 clinical charts of patients admitted from 1995 to 2008 were reviewed. The median (range) age of patients at diagnosis was 4 years old (0.2 to 16); 54% were males; 23% had a family history of CF; 26% had been diagnosed erroneously as tuberculosis, and 60% were first diagnosed at the INER, with no previous suspicion of the presence of this disease.
Conclusion: Patients attending the INER have complications of CF inasmuch as diagnosis is made at a late stage in the course of the disease.
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