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ISSN 0185-3252 (Print)
Revista de la Asociación Médica del Centro Médico ABC

2009, Number 3

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An Med Asoc Med Hosp ABC 2009; 54 (3)

Dexmedetomidine as pre-anesthetic to attenuate hemodynamic response of pneumoperitoneum

Urías E, Covarrubias JA, Sánchez JP, Martínez TR, Montoya T, Cardona G, Jiménez A, Jiménez A

Language: Spanish
References: 16
Page: 161-165
PDF size: 53.57 Kb.


ABSTRACT

Due to the increasing number of laparoscopic techniques for general surgery and gynecologic procedures, it is necessary to count on an multimodal anesthetic technique that allows the reduction of the hemodynamic changes caused by the pneumoperitoneum and that lead, to improve the functionality and recovery of the patients. We studied two groups of 20 patients each (First group «Dexmedetomidine», second group «Control») between 18 and 60 years old, Dexmedetomidine was administered to the first group as a pre-anesthetic. The second group was not. We measured variables like mean arterial tension, heart rate, oxygen saturation and the carbon dioxide level at the end of the expiration. Making a comparison between both groups, we found similar results in both, not finding significant statistical differences, even though the group with Dexmedetomidine required less opioid doses than the control group, and no hemodynamic changes occurred in any patients. In control group, 3 patients had hypertensive crisis. We consider it necessary to run more studies with larger samples at different doses. Finally, we concluded that Dexmedetomidine reduces anesthetic requirements of other agents, but it doesn´t help to diminish hemodynamic changes produced by the pneumoperitoneum at the doses we used.


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