Castro-Barrientos L, Gutiérrez-Farfán I, Alonso-Lujan L, Chamlati-Aguirre L, Paniagua-Pérez R, Sánchez-Chapul L, Martínez-Castro J, Peñuelas-Romero K, Zavala-Hernández C, Reyes-Cadena S

Language: Spanish
References: 26
Page: 140-147
PDF size: 59.61 Kb.

ABSTRACT

Congenital infection by cytomegalovirus (CMV) and Epstein-Barr (EB) can cause general sensorineural hearing loss. Objective: To determine the presence of CMV and EB among children as an etiologic factor in sensorineural hearing loss. Methods: We performed and audiological evaluation (audiometry, tympanometry, and stapedial reflexes) in order to determine the degree of hearing loss by ink differential, flow cytometry, and determined frequency of lymphocyte t, CD3, CD4, CD8, antiviral antibodies CMV, EB for IgG, and IgM in 12 patients. Results: We observed sensorineural hearing loss which was severe to profound, tympanography curves were reported as normal in 83% of the patients. Stapedial reflexes were absent in all patients. In 16% of the patients computer tomography imaging of cranium reported cortex atrophy. Frequency of lymphocyte B and lymphocyte CD8+ increase (p ‹ 0.05). In 100% of the patients the presence of CMV and IgG was determined, and IgM in 16%. Conclusions: The results demonstrated the presence of CMV virus and EB for IgG which may be associated with internal hearing loss damage as possible etiology in sensorineural hearing loss.

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