Ulloa RE, Arroyo E, Nicolini H

Language: Spanish
References: 20
Page: 50-55
PDF size: 160.40 Kb.

ABSTRACT

Obsessive-compulsive disorder (OCD) has a frequency of 0.2%-5% in clinical population of children and adolescents. Although it shares characteristics, such as severity and response rate to treatment, with the adult disorder, the etiology and physiopathology of pediatric OCD has not been completely understood. The word PANDAS (Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal Infections) includes disorders such as OCD and Tourette syndrome produced after an streptococcal infection. The main characteristic of PANDAS is the abrupt onset or exacerbation of symptoms, and their remission after the infection is controlled. Comorbid symptoms (anxiety, hyperactivity and conduct disorders) are frequently observed and disappear with the OCD symptoms. The evaluation of these patients requires to determine if other psychiatric symptoms are present, as well as a complete physical examination. Antibodies (antistreptococcal and D8/17) are useful for the diagnosis. PANDAS patients show little respo nse to the traditional management of OCD; however, immunotherapies emerge as a good choice for treatment.

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