2001, Number 1
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Salud Mental 2001; 24 (1)
Dermatoglyphic study of positive and negative symptoms in schizophrenia
Páez F, Apiquián R, Fresán A, Puig A, Orozco B, De la Fuente JM, Sidenberg , Nicolini H
Language: Spanish
References: 28
Page: 28-32
PDF size: 133.88 Kb.
ABSTRACT
The study of dermal ridges in schizophrenia has been extensive, but only recently has fluctuating asymmetry been described. This study relates dermatoglyphic patterns with the specific positive and nega- tive symptoms of the disease in 72 DSM-III-R defined schizophre- nia and 72 normal unrelated ethnically matched controls. Schizo- phrenic subjects had significant lower ridge counts in both hands. Fluctuating asymmetry in the a-b ridge counts was significantly lower in schizophrenic subjects (0.50 vs 0.70, p‹0.05). The positive and negative symptom scale (PANSS) was used to determine symptom severity. Schizophrenics with predominantly negative symptoms showed significantly lower counts and higher fluctuating asymmetry than schizophrenics with positive symptoms. Our study showed findings congruent with the hypothesis that schizophrenia could be related to central nervous system develop- mental abnormalities.
REFERENCES
AMERICAN PSYCHIATRIC ASSOCIATION: Diagnostic and Statistical. Manual of Mental Disorders (3rd ed., revised) (DSM-III-R). APA, Washington, 1987.
ANDREASEN NC, FLAUM M, SWAYZE VW: Positive and negative symptoms in schizophrenia: a critical reappraisal. Archives of General Psychiatry, 47: 615-621, 1990.
ANDREASEN NC: Linking mind and brain in the study of mental illnesses: A project for a scientific pychopathology, Science, 275:1586-1593, 1997.
APIQUIAN R, FRESAN A, NICOLINI H: Evaluación de la psicopatología. Escalas en español. First Edition. Edit. Ciencia y Cultura Latinoamericana. México, 2000.
BABLER WJ: Embryonic Development of Epidermal Ridges and Their Configurations in Dermatoglyphics: Science in Transition, vol 2. Plato CC, Garruto RM, Schaumman BA (eds.). Wiley- Liss: 95-112, New York, 1991.
BALGIR RS, MURTHY RS, WIG NN: Manic-depressive psychosis and schizophrenia: A dermatoglyphic study. British J Psychiatry, 136:558-61, 1980.
BARTA E, PEARLSON GD, POWERS RE, RICHARDS SS, TUNE LE: Auditory hallucinations and smaller superior temporal gyrus volume in schizophrenia. American J Psychiatry, 147(11):1457-1462, 1990.
BRACHA HS, TORREY EF, GOTTESMANI I, BIGELOW LB, CUNNIFF C: Second-trimester markers of fetal size in schizophrenia: a study of monozygotic twins. American J Psychiatry, 149:1355-1361, 1992.
CROW TJ: Molecular pathology of schizophrenia: more than one disease process. British Medical J, 28:66-68, 1980.
CUMMINGS C, FLYNN D, PREUS M: Increased morphological variants in children with learning disabilities. J Autism Developmental Diseases, 12:373-383, 1982.
DAVIS JO, PHELPS JA, BRACHA HS: Prenatal development of monozygotic twins and concordance for schizophrenia. Schizophrenia Bulletin, 21:357-366, 1995.
FANANAS L, GUTIERREZ B, BOSCH S, CARANDELL F, OBIOLS JE: Presence of dermatoglyphic ridge dissociation in a schizotypy-affected subject in a pair of discordant MZ twins. Schizophrenia Research, 21: 125-127, 1996.
GUTIERREZ B, VAN OS J, VALLES V, GUILLAMAT R,CAMPILLO M, FANANAS L: Congenital dermatoglyphic malformations in severe bipolar disorder. Psychiatry Research, 78:133-140, 1998.
GOTTESMMAN II: Is schizophrenia inherited genetically? Schizophrenia Genesis The Origins of Madness, 93. WH. Freeman and Company, New York, 1994.
HAFNER H, MAURER K: Are there two types of schizophrenia? True onset and sequence of positive and negative symptoms prior to first admission. In: Marneros A, Andreasen NC, Tsuang MT (eds). Negative versus Positive Schizophrenia. Springer-Verlaf Inc: 134-159, Berlin, 1990.
HOLT S: The Genetics of Dermal Ridges. Charles C. Thomas Publisher, Springfield, 1968.
KAY SR, FISZBEIN A, OPLER LA: The Positive and Negative Syndrome Scale (PANSS) for schizophrenia. Schizophrenia Bulletin, 12(2):261-276, 1987.
KAY SR, FIZBERN A, VITAL-HERNE M, SILVA L: Positive and negative syndrome scale-Spanish adaptation. J Nervous Mental Disease, 178:510-517, 1990.
MARKOW TA, WANDLER K: Fluctuating dermatoglyphic asymmetry and the genetics of liability to schizophrenia. Psychiatry Research, 19:323-328, 1986.
MARKOW TA, GOTTESMAN I: Fluctuating dermatoglyphic asymmetry in psychotic twins. Psychiatry Research, 29:37- 43, 1989.
MELLOR CS: Dermatoglyphic evidence of fluctuating asymmetry in schizophrenia. British J Psychiatry, 160:467-472, 1992.
ROSA A, FANANAS L, BRACHA SH, TORREY FE, VAN OS J: Congenital dermatoglyphic malformations and psychosis: a twin study. American J Psychiatry, 157:9, 2000.
SALAMANCA F: Citogenética Humana. 1st. Edition. Edit.Panamericana. México, 1990.
SRINIVASA M, WIG NN: Dermatoglyphics in schizophrenia: The relevance of positive family history. British J Psychiatry, 130(56-s):56-58, 1977.
TANDON R, GOLDMAN R, GOODSON JF: Mutability and relationship between positive and negative symptoms during neuroleptic treatment in schizophrenia. Biological Psychiatry, 27:1323-1326, 1990.
VAN OS J, FANANAS L, CANNON M, MACDONALD A, MURRAY R: Dermatoglyphic abnormalities in psychosis; a twin study. Biological Psychiatry, 41:624-626, 1997.
VAZQUEZ- BARQUERO JL, GAITE L, ARTAL J,DIEZ MANRIQUE JF, HERRERA-CASTANEDO S, WILLIAMS Y: Report on the Spanish translation of the SCAN, shedules and glossary. Informe a la Organización Mundial de la Salud. Unidad de Investigación en Psiquiatría Social de Cantabria, Santander, 1992.
WORLD HEALTH ORGANIZATION SCAN: Schedules for Clinical Assessment in Neuropsychiatry. Schedules. WHO Geneva, 1992.