1999, Number 3
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Rev Biomed 1999; 10 (3)
The ímportance of the characterisation of Trypanosoma cruzi strains
Guzmán-Marín ES, Zavala-Castro JE, Acosta-Viana KY, Rosado-Barrera ME
Language: Spanish
References: 38
Page: 177-184
PDF size: 150.77 Kb.
ABSTRACT
Trypanosoma cruzi (T. cruzi) is haemoflagelate protozoo considered to be the causal agent of Chagas’ disease and it is transmitted to its mammalian host by insect vectors of the genous Triatoma.
T. cruzi presents a natural pleomorphism wich is believed to be responsible for the difference in severety in which the disease occurs in the human host compared to other mammals. Considering this aspect, there are various studies on the characterisation of the strains of
T. cruzi, covering biological, biochemical and molecular aspects of the protozoo, in order to stablish a method of classification of the different strains of
T. cruzi. In this way, the strains which belong to one group share these aspects and therefore one strain could represent that group, simplifying the studies to be carried out.
This review aims to give a panorama of the different methods to characterisation of
T. cruzi, in order to attempt to group them for a better study and control.
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