1999, Número 3
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Rev Biomed 1999; 10 (3)
Importancia de la caracterización de cepas de Trypanosoma cruzi
Guzmán-Marín ES, Zavala-Castro JE, Acosta-Viana KY, Rosado-Barrera ME
Idioma: Español
Referencias bibliográficas: 38
Paginas: 177-184
Archivo PDF: 150.77 Kb.
RESUMEN
El
Trypanosoma cruzi (T. cruzi) es un protozoario hemoflagelado, considerado el agente causal de la enfermedad de Chagas y es transmitido a los hospederos mamíferos por medio de insectos vectores del género
Triatoma. El
T. cruzi presenta un pleomorfismo natural, al cual se ha atribuido a la diferencia de severidad con que se presenta la enfermedad en el hospedero humano y otros mamíferos. Considerando este aspecto han sido varios los trabajos sobre caracterización de cepas de
T. cruzi, abarcando aspectos biológicos, bioquímicos y moleculares para poder establecer un método de clasificación de las diferentes cepas de dicho parásito, de manera que las cepas que pertenezcan a un mismo grupo compartan estos aspectos y así una cepa pudiera ser representativa de ese grupo, simplificando los estudios a realizar.
Esta revisión pretende dar un panorama de los diferentes métodos de caracterización de las cepas de
T. cruzi, para tratar de agruparlas para su mejor estudio y control.
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