medigraphic.com
Centro de Investigaciones Regionales Dr. Hideyo Noguchi, Universidad Autónoma de Yucatán

2002, Number 1

<< Back Next >>

Rev Biomed 2002; 13 (1)

Frequency of Chlamydia Pneumoniae antibodies in the rural population of Yucatan, Mexico.

Jiménez-Delgadillo B, Vado-Solís I, Laviada-Molina H, Zavala-Velázquez J

Language: Spanish
References: 15
Page: 9-13
PDF size: 26.24 Kb.


ABSTRACT

Introduction. Chlamydia pneumoniae (CP) respiratory infections produce a wide spectrum of diseases, from almost asymptomatic high respiratory tract affection to serious pneumonia. This intracellular bacterium has also been associated with atheroesclerotic cardiovascular disease, making its epidemiological study more attractive. The aim of this study was to obtain preliminary information of the seroepidemiologic behavior of CP infection in an adult sample from the state of Yucatan, Mexico. Material and methods. Blood samples were obtained from 85 healthy subjects (42 male, 43 female) over 20 years old. The number of subjects was adjusted by age decades and gender, to be proportionally true to the structure of the population of the region, according to the official statistics of the state. CP specific antibodies IgA were measured by immunoenzimatic assay (ELISA). The blood samples came from 52 diferent settlements of the Yucatan state randomly selected. Results. Among the 85 blood sa mples, 34 (40 %) were seropositive. There was a higher frequency in the younger subjects sampled and a lower rate in the older, however this trend was not statistically significant. Discussion. There is a high frequency of seropositivity in the adult population of Yucatan, Mexico, similar to the reported data of the literature in other countries, suggesting also a high prevalence of (symptomatic or asymptomatic) respiratory diseases produced by CP. This high frequency is more relevant as there is mounting evidence to suggest that Chlamydia pneumoniae might play a role in atheroesclerosis.


REFERENCES

  1. 1.- Kuo C, Grayston T. Factors afecting viability and growth in He La 229 cells of chlamydia sp. strain TWAR. J Clin Microbiol 1988; 26 : 812-5.

  2. 2.- Grayston JT, Campbell LA, LA, Kuo CC. A new respiratory patogen: Chlamydia pneumoniae strain TWAR. J Infect Dis 1990; 161: 618-25.

  3. 3.- Saiku P. Epidemiology of Chlamydia pneumoniae in atheroesclerosis. Am Heart J 1999; 138: 500-3.

  4. 4.- Stamm W. Infecciones por Chlamydia. En: Fauci AS,Braunwald E, Isselbachor KJ, Wilson JD, Martin JB, Kasper DL, Hauser SL, Longo DL, editores. Harrison. Principios de Medicina Interna, 14th edición, México: McGraw-Hill Interamericana; 1999. p. 1209-19.

  5. 5.- Kleemola M, Saikku P, Visacorpi R, Wang SP, Grayston JT. Epidemics of pneumonia caused by TWAR, a new Chlamydia organism , in military trainees in Finland. J Infect Dis 1985; 151: 230-6.

  6. 6.- Muhlestein J. Chronic infection and coronary artery disease. Science & Medicine 1998; Nov-Dec: 16-25.

  7. 7.- Wong YK, Gallagher PJ, Ward ME. Chlamydia pneumoniae and atheroesclerosis. Heart 1999; 81: 232-8.

  8. 8.- Dirección General de Estadística, Informática y Evaluación, Secretaría de Salud. México: SSA; 1997.

  9. 9.- Instituto Nacional de Estadística, Geografía e Informática. Yucatán. Conteo de Población y Vivienda. México: INEGI; 1995.

  10. 10.- Leowattana W, Mahanonda N, Bhuripunyo K,Leelarasamee A, Pokum S, Suwimol B. The prevalence of Chlamydia pneumoniae antibodies in Thai patients with coronary artery disease. J Med Assoc Thai 1999; 82: 792- 7.

  11. 11.- Miyashita N, Toyota E, Sawayama T, Matsumoto A,Mikami Y, Kawai N, et al. Association of chronic infection of Chlamydia pneumoniae and coronary heart disease in the Japanese. Intern Med 1998; 37: 913-6.

  12. 12.- Canul G, Vargas L, Laviada H. Los yucatecos: ¿De que se enferman y mueren? Cuad Nutr 1998; 21: 20-4.

  13. 13.- Arroyo P, Pardío L, Fernández V, Vargas L. Obesity and cultural environment in the Yucatan region. Nutr Rev 1999; 57:S78-S83.

  14. 14.- Laviada H, Vargas L, Arroyo P, Pardío J, Fernández V. Epidemiología de Diabetes Mellitus en la población urbana de Yucatán. Revista de Endocrinología y Nutrición 1999; 7 (Supl): 109.

  15. 15.- Valles V, Laviada H, Vargas L, Arroyo P, Fernández V, Pardío P. Epidemiología de dislipidemias en la población Urbana de Yucatán. Revista de Endocrinología y Nutrición 1999; 7 (Supl): 110.




2020     |     www.medigraphic.com