2009, Number 4
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Med Crit 2009; 23 (4)
Procalcitonin as an early diagnostic marker for septic shock
Montoya GC, Hernández LA, Villalobos SJA, Aguirre SJ, Franco GJ
Language: Spanish
References: 21
Page: 211-217
PDF size: 108.26 Kb.
ABSTRACT
Introduction: Procalcitonin (PCT) in early stages of shock, it may differentiate between septic and other causes of shock allowing an early treatment.
Objective: The objective of our study was to determine PCT usefulness as an early diagnostic marker for septic shock.
Methods: Prospective, longitudinal, observational study.
Results: 108 patients with an initial diagnosis of shock were included. PCT was determined at admittance and 5 days later. Sedimentation Rate (SR), C-reactive protein (CRP), leukocytes, APACHE II Score and SOFA score were also obtained.
At admittance, patients with septic shock presented higher PCT, SR, CRP and leukocyte values than other shock from other causes: PCT 4 (3-5)
vs 0 (0-0) of septic shock
vs. others respectively (p ‹ 0.01); SR 20 (15-25) in septic shock
vs 9 (7-14) and p value ‹ 0.01; CRP 15 (10-19)
vs 7 (4-10) respectively (p ‹ 0.01).
Conclusion: As expected, this study demonstrates that elevations of PCT in shock patients at admittance, is the best way to differentiate between septic shock and other causes of shock.
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