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Anales de la Sociedad Mexicana de Oftalmología y Archivos de la Asociación Para Evitar la Ceguera en México

2009, Number 4

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Rev Mex Oftalmol 2009; 83 (4)

Factores asociados con rechazo a trasplante de córnea, por grupos de pronóstico

Sánchez-Cornejo M, Olivares-Morales OE, Lima-Gómez V, Razo-Blanco HDM, Pérez-Taibo C

Language: Spanish
References: 23
Page: 217-220
PDF size: 88.80 Kb.


ABSTRACT

Purpose: To determine the risk factors for rejection in patients undergoing penetrating keratoplasty
Materials and methods: Observational, longitudinal, retrospective, analytic and open study, of patients of the Hospital Juarez de México from January 2003 to November 2006. We included patients with penetrating keratoplasty with any corneal disease, age and gender, and followed them up for 1 year. According to the diagnosis each eye was assigned to one of four groups of prognosis. The clinical characteristics of risk for rejection in eyes were identified, and the difference between proportions analyzed by rates of X2 and odds ratio.
Results: 110 eyes were evaluated; patients between 4 and 90 years old, 42 eyes corresponding to group 1 (38.2%), 52 to group 2 (47.3%), 9 to group 3 (8.2%) and 7 to group 4 (6.4%), 57 eyes had immunologic failure (54.1%). Vascularisation was the unique variable with significant difference (p=0.01) odds ratio (9.75), didn’t find significant difference in immunology failures between groups (p›0.05).
Conclusions: The factor associate significantly with rejection was anatomical, not etiological. It is necessary to standardize the preoperating measurement of this factor to value its utility as a predicting factor.


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