2009, Number 2
Adenosquamous carcinoma of the duodenum. Case report
Mier MP, Lazos OM
Language: Spanish
References: 0
Page: 91-95
PDF size: 248.42 Kb.
ABSTRACT
Adenoesquamos carcinomas (ASC) of the duodenum are rare. As primary neoplasm of the duodenum, the ASC are the second neoplasm in frequency after the usual adenocarcinomas. They have been reported in all portions of the gastrointestinal tract, including the gastroesophageal junction and the anal canal, where glandular and squamous epithelium are juxtaposed. This is the report of a 75-year-old woman, with systemic arterial hypertension and diabetes, who entered the hospital with abdominal pain, fever, jaundice, coluria, pruritus and loss of weight. An open cholecystectomy was performed; obstruction, dilatation of extrahepatic bile ducts and a tumor of the biliopancreatic system were observed. She died with the clinical diagnosis of pancreatobiliary neoplasm. The autopsy revealed two ASC located in the second and third portions of the duodenum, furthermore, a node localized in the Vater ampulla, which caused parcial obstruction and dilatation of extrahepatic bile ducts was found. Only 8 cases of ASC of the small bowel have been reported, one of them in the duodenum. Most the patients with ASC are females around 60 years-old. There is an association with chronic inflammation or metaplasia of the intestinal mucosa.