2009, Number 2
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Rev Med Hosp Gen Mex 2009; 72 (2)
Chlamydia trachomatis prevalence in adults with chronic follicular conjunctivitis
Vázquez-Maya L, Ramírez-Villagrán B, Vázquez-Campuzano R, Villavicencio-Torres A
Language: Spanish
References: 21
Page: 73-77
PDF size: 120.75 Kb.
ABSTRACT
Introduction: Chlamydia keratoconjunctivitis in adults (CKA) represents the ocular manifestation of the venereal disease. Untreated cases may have six to 18 month chronic courses; its evolution is related to the patient’s immune response. We sought to determine, a) the prevalence of CKA in cases with chronic follicular conjunctivitis (CFC), b) the severity of the condition and, c) the influence of factors that could increase the risk of Chlamydia trachomatis (CT) infection.
Material and methods: In a prospective, transversal, interventional study, conjunctival swabs were done in 50 adults with CFC to detect
C. trachomatis by immunofluorescence in the Department of Ophthalmology of the Hospital General de México.
Results: Eighteen women and 11 men (1.6:1) had positive swabs for
Chlamydia trachomatis; 19 of the 29 had corneal involvement, mainly pannus. Risk factors included ages from 20 to 29 and over 60 years, active sexual relations before the age of 15, no use of contraception and the presence of genitourinary symptoms.
Conclusions: In our clinical material. 58% of CFC are produced by
C. trachomatis. CKA is the manifestation of a systemic disease. Barrier contraception provides partial protection against Chlamydia trachomatis.
REFERENCES
Grayson. Enfermedades de la córnea. Capítulo 6 y 7. 4a ed. Philadelphia, PA: Mosby; 1999. p. 117-118, 142-152.
González-Almaraz, Pineda-Cárdenas. Diagnóstico diferencial de la queratoconjuntivitis folicular. Rev Mex Oftalmol 1987; 61 (5): 233-237.
González-Almaraz, Pineda-Cárdenas. Etiología de las queratoconjuntivitis. Rev Mex Oftalmol 1987; 61 (5): 233-237.
Thylefors B, Negrel AD, Pararajasegaram R. La surreillance epidemiologique du tracome: Bilan et perspective. Rey nt Trachome 1992; 69: 107-114.
Goldschmidt P, Vanzzini Zago V, Diaz Vargas L, Espinoza Garcia L, Morales Montoya C, Peralta B et al. Chlamydia trachomatis in the conjunctiva of children living in three rural areas in Mexico. Rev Panam Sal Pub 2007; 22 (1): 29–34.
Krachmer, Mannis, Holland. Cornea. 2nd ed. Elsevier-Mosby 2005; p. 639-645.
Dawson CR, Schachter J. TRIC agent infection of the eye and genital tract. Am J Ophthamol 1967; 63: 1288-1289.
Jones BR. Ocular syndromes of TRIC virus infection and their possible genital significance. Br J Vener Dis 1964; 40: 3-15.
Viswalingam ND, Wishart MS, Woodland RM. Adult chlamydial ophthalmia (paratrachoma). Br Med Bull 1983; 39: 123-127.
Creuzot-Garcher C. Inclusion conjunctivitis in adults. J Fr Ophthalmol 1999; 22: 577-580.
López M, Arteaga G, Zamora A et al. Factores de riesgo y secuelas reproductivas asociados a la infección por Chlamydia trachomatis en mujeres infértiles. Sal Pub Mex 2003; 45: 672-680.
Dawson CR. Eye disease with chlamydial infections. In: Oriel D, Ridway G, Schachter J, Taylor-Robinson D, Ward M (eds). Chlamydial infection. Cambridge, Cambridge: University Press; 1986. p. 135-144.
Stenberg K, Mardh PA. Chlamydial conjunctivitis in neonates and adults. Acta Ophthalmol 1990; 68: 651-657.
Acosta-Cazares B. Prevalence and risk factors for Chlamydia trachomatis infection in low- income rural and suburban populations of Mexico. Am J Sex Trans Dis 1996; 23: 283– 288.
Malathi J et al. A hospital based study on the prevalence of conjunctivitis due to Chlamydia trachomatis. Ind J Med Res. 2003 117:71-5
Kirk R, Wilhelmus MD, Nettie M et al. Conjunctival cytology of adult chlamydial conjunctivitis. Arch Ophthalmol 1986; 104: 691-693.
González-Almaraz, Pineda-Cardenas. Diagnóstico citológico de la conjunctivitis por Chlamydia trachomatis. Rev Mex Oftalmol 1987; 61: 179-184.
Spencer. Ophthalmic pathology: An atlas and textbook (in CD-ROM). American Academy of Ophthalmology; 2007-2008 vol 1, chap 3.
Elnifro, Elfath M et al. Polymerase chain reaction for detection of Chlamydia trachomatis in conjunctival swabs. BJ Ophthalmol 1997; 81: 497-500.
Basualdo JA, Huarte L. Conjuntivitis folicular debida a Chlamydia trachomatis. Medicina, Buenos Aires, 2001; 61: 397-400.
Muñoz María, Caballero Patricia. Conjuntivitis folicular por Chlamydia trachomatis: frecuencia y pruebas diagnósticas. Rev Peru Med Exp Sal Pub 2007; 24: 286-289.