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Centro de Investigaciones Regionales Dr. Hideyo Noguchi, Universidad Autónoma de Yucatán

2001, Number 4

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Rev Biomed 2001; 12 (4)

Mycoplasmas and their medical importance.

Rivera-Tapia JA, Cedillo-Ramírez ML, Vega-Benítez M

Language: Spanish
References: 68
Page: 262-271
PDF size: 61.28 Kb.


ABSTRACT

In 1898 mycoplasmas were described as the smallest self-replicating bacteria, these microorganisms exhibit special morphologic, metabolic and molecular characteristics. Their role in human diseases has generated interest since they are frequently related with chronic acute and even fatal diseases during the everyday clinical practice. Their distribution in hosts is diverse, since they have been isolated from fish, reptiles, birds, mammals and humans. In this last host they have been isolated from diverse anatomical sites, in both healthy and sick subjects. Their presence has been observed in respiratory and genitourinary tract, neurological complications as well as in blood. Special attention has been paid to their possible relationship as a cofactor in the progression of the Acquired Immunodeficiency Syndrome. The role of Mycoplasma fermentans in several diseases has been studied during the last twenty years. Several studies are being carried out in order to determine its role as a pathogen and the mechanism it uses to interact with the hosts cells, to survive inside phagocytes cells, its immunomodulatory ability and especially its antigenic variation.


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