medigraphic.com
Centro de Investigaciones Regionales Dr. Hideyo Noguchi, Universidad Autónoma de Yucatán

2001, Number 2

<< Back Next >>

Rev Biomed 2001; 12 (2)

Can mosquitoes transmit Human Immunodeficiency Virus?

Ayora-Talavera G, Manrique-Saide PC

Language: Spanish
References: 22
Page: 130-136
PDF size: 38.69 Kb.


ABSTRACT

Transmission of human immunodeficiency virus (HIV) is known to occur perinatally, through sexual contact, and after exposure to infected blood or blood products among others. The question whether the possibility exists of transmission of HIV by hematophagous insects from infected to uninfected persons is a point of very intensive discussion. The classical routes of pathogen transmission by blood-sucking arthropods are either “mechanical“ or “biological”. Both ways are rejected, the latter since no replication of the retroviruses in the vector exists and its survival in the arthropod is very limited. The persistence of HIV in an insect or on its mouthparts is one of many factors necessary for mechanical transmission in nature. The risk of insect transmission of HIV appears to be extremely low or non-existent. This reviews article summarise the scientific evidence and reasons to conclude why HIV transmission by mosquitoes is impossible.


REFERENCES

  1. Dimond JB, Lea AO, Hahnert WF, de Long DM. The amino acids required for egg production in insects. Proceedings of the Tenth International Congress of Entomology, Montreal, Canada 1956; 2: 135-137.

  2. Hocking B. Blood-sucking behaviour of terrestrial arthropods. Ann Rev Entomol 1971; 16: 1-26.

  3. Leake CJ. Arbovirus-mosquito interactions and vector specificity. Parasit Today 1992; 8: 123-128.

  4. Piot P, Schofield CJ. No evidence for Arthropod transmission of AIDS. Parasit Today 1986; 2: 294.

  5. Booth, W. AIDS and insects. Science 1987; 237: 355-6.

  6. Leishman K. AIDS and insects. The Atlantic Monthly 1987; Sept: 56-72.

  7. Miike L. Do insects transmit AIDS? In: AIDS related issues. Health Program Office of Technology Assessment United States Congress. Washington, D.C. 1987; 1-43.

  8. Friesen H, Danaya R, Doonar P, Kemiki A, Lagani W, Mataio G, et al. Assessment of HIV/AIDS knowledge, attitudes and behaviour of high school students in Papua New Guinea. PNG Med J 39: 208-13.

  9. Ambati BK, Ambati J y Rao AM. Dynamics of knowledge and attitudes about AIDS among the educated in southern India. AIDS Care 1997; 9: 319-30.

  10. Whiteside ME, Withum D, Tavris D, MacLeod C. Outbreak of no identifiable risk acquired immunodeficiency syndrome (AIDS) in Belle Glade, Florida. First International Conference on AIDS. Atlanta April 17th, E.U.A 1985.

  11. Castro KG, Lieb S, Jaffe HW, Narkunas JP, Calisher CH, Bush TJ, et al. Transmission of HIV in Belle Glade, Florida: Lessons for other communities in the United States. Science 1988; 239: 193-7.

  12. Mann JM, Francis H, Quinn T. Surveillance for AIDS in a Central Africa city: Kinshasa, Zaire. JAMA 1986; 255: 3255-9.

  13. Coffin JM. Retroviridae and their replication, En Fields BN, Knipe DM eds. Fields Virology. New York: Raven Press; 1999. p. 961-1034.

  14. Langley PA. Pathogen transmission in relation to feeding and digestion by haematophagous arthropods. Acta Trop XXXII 1975; 2: 116-23.

  15. Foil LD, Issel J. Transmission of retroviruses by arthropods. Annu Rev Entomol 1991; 36: 355-81.

  16. Jupp PJ, Lyons SF. Experimental assesment of bedbugs (Cimex lenticularis and Cimex hemipterus) and mosquitoes (Aedes aegypti formosus) as vectors of human immunodeficiency virus. AIDS 1987; 1: 171-4.

  17. Becker JL, Hazan U, Nugeyre MT, Rey F, Spire B, et al. Infection of insect lines by HIV, agent of AIDS, and evidence for HIV proviral DNA in insects. CR Acad Sci Paris 1986; 303: 303-6.

  18. Chermann JC, Becker JL, Hazan U, et al. HIV related sequences in insects from Central Africa. 3rd International Conference on AIDS. Washington D.C. E.U.A. June 1st, 1987.

  19. Srinivasan A, York D, Bohan C. Lack of HIV replication in Artrhopod cells. Lancet 1987; 1:1094-5.

  20. Ribeiro JMC. Blood-feeding arthropods: live syringes or invertebrate pharmacologists?. Infect Agents Dis 1995; 4:143-52.

  21. Foil LD. Tabanids as vectors of disease agents. Parasit Today 1987; 5: 88-96.

  22. Hardy JL. Susceptibility and resistance of vector mosquitoes. In: Monath TP, ed. The arboviruses: ecology and epidemiology, Vol I. Boca Raton: CRC Press; 1988. p. 87-126.




2020     |     www.medigraphic.com