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Centro de Investigaciones Regionales Dr. Hideyo Noguchi, Universidad Autónoma de Yucatán

2003, Number 4

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Rev Biomed 2003; 14 (4)

Prevalence of IgG antibodies against Toxoplasma gondii in Cuban blood donors

Martín-Hernández I, García-Izquierdo SM

Language: Spanish
References: 21
Page: 247-251
PDF size: 32.46 Kb.


ABSTRACT

Introduction. Toxoplasmosis is a human infection disease that occurs worldwide and its frequency varies among different geographical zones and eating habits. In Cuba this infection is common, although the presence of specific antibodies varies between 50-75% in relation with the geographical area and the detection method employed.
Materials and methods. A seroepidemiological study of 922 blood donors’ serum samples from the Municipality of Marianao, Havana City, was carried out with the purpose of measuring concentrations of anti-T. gondii IgG antibodies (UI/mL) and the behaviour of seropositivity with age. The heterogeneous immunoenzimatic assay UMELISA Toxoplasmaâ was used for the detection of IgG antibodies to Toxoplasma gondii in serum samples.
Results. A seroprevalence to Toxoplasma gondii of 73,43% was found, additionally an increase in seropositivity with age and a decrease of reactivity percentages with the increase of titles were observed. The presence of specific IgG antibodies showed similar behaviour for the age groups 20-24, 25-29, and 30-34 years old with no significant difference between them (p›0,05). In the same way, they differ significantly (p‹0,05) from to 35-39 and 40-or more year old age groups, although these age groups showed no difference between each other.
Discussion. The high prevalence of anti-Toxoplasma gondii IgG antibodies in the Municipality of Marianao lead us to consider this province as an intensive endemic zone.


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