Canún-Serrano S, Reyes-Pablo AE, Sánchez-Sánchez M, Jaime-Gómez L, Centeno-Morones FJ, Falcón-Bernal I, Legorreta-García MC, Valdés-Hernández J

Language: Spanish
References: 19
Page: 115-120
PDF size: 80.23 Kb.

ABSTRACT

Background: In 1992, the United States Public Health Service, the American Academy of Pediatrics, the Centers for Disease Control and Prevention, and the United States Institute of Medicine recommended periconceptional intake of 400 μg of folic acid (FA) in order to reduce the risk of neural tube defects (NTD) by 70%. Our objective was to assess among pregnant women the periconceptional intake of FA and to assess the level of knowledge among health professionals regarding the benefits associated with FA intake as a preventive measure of NTD.
Methods: We designed a prospective and cross-sectional study to assess certain sociodemographic and reproductive health characteristics, knowledge of periconceptional intake, benefits of FA intake among pregnant women and among health workers. Descriptive statistics was employed.
Results: From 200 pregnant women, only 1.7% had taken 400µg doses of periconceptional FA. Among participating health care personnel only 10.17% knew about the benefits of periconceptional intake of 400µg of FA.
Conclusions: Periconceptional intake of FA among our sample of pregnant woman was very low and knowledge of its benefits among health professionals was also scarce.

REFERENCES

1. Gupta H, Gupta P. Neural tube defects and folic acid. Indian J Pediatr 2004; 41:577-586.

2. Rodríguez-Morán M, Guerrero-Romero JF, Parra-Quezada M, Segura-Pineda MJ, Levario-Carrillo M, Sotelo Ham EI. Deficiencia de folatos y su asociación con defectos de cierre del tubo neural en el norte de México. Salud Publica Mex 1998;40:474-480.

3. Botto LD, Moore CA, Khoury MJ, Erickson D. Neural-Tube Defects. New Engl J Med 1999;341:1509-1519.

4. García-Morales MA, Limón-Luque L M, Barrón-Vallejo J, González-Morales ME, Kably-Ambe A. Uso periconcepcional de ácido fólico en la prevención de defectos de cierre de tubo neural: conceptos actuales. Ginecol Obstet Mex 1996:418-421.

5. Green NS. Folic acid supplementation and prevention of birth defects. Trans- HHS Workshop: Diet, DNA, methylation processes and health. March of Dimes. J Nutr 2002(Suppl 8):2356S-2360S.

6. Olney RS, Mulinare J. Trends in neural tube defect prevalence, folic acid fortification, and vitamin supplement use. Seminars in Perinatology 2002;26:227-285.

7. Desposito F, Cunniff C, Frias JL, Panny SR, Trotter TL, Wappner RS. American Academy Pediatrics, Comitte on Genetics. Folic Acid for the prevention of neural tube defects. Pediatrics 1999;104:325-327.

8. Morales JJ, Luna L, Mutchinick O. Epidemiología de las malformaciones congénitas. En Guizar Vázquez. Genética Clínica. Diagnóstico y manejo de las enfermedades hereditarias México: El Manual Moderno; 2001. pp. 345-351.

9. Mancebo-Hernández A, González-Rivera A, Diaz-Omaña L, López-Alquicira M, Domínguez-Viveros W, Serrano-Sierra A. Panorama Epidemiológico en México (I de II). Acta Pediatr Mex 2008;29:41-47.

10. Berry R, Li Z, Erickson D, Li S, Moore CA, Wang H, Mulinare J, Zhao P et al. Prevention of neural tube defects with folic acid in China. N Engl J Med 1999;341:1485-1490.

11. Joint SOGC-Motherisk Clinical Practice Guideline. Pre-Conceptional Vitamin/ Folic Acid Supplementation 2007: The use of Folic Acid in Combination with a Multivitamin Supplement for the Prevention of Neural Tube Defects and Other Congenital Anomalies. J Obstet Gynecol Can 2007;12:1003-1026.

12. http://sinais.salud.gob.mx/publicaciones/index.html.

13. Sen S, Manzoor A, Deviasumathy M, Newton C. Maternal knowledge, attitude and practice regarding folic acid intake during the periconceptional (periconceptional) period. Public Health Nutrition 2001;4:909-912.

14. Binns C, Scott J, Nwafor N, Graham K, Oddy W, Lee A. Which mothers take folic acid and folate containing foods? Asia Pac. J. Clin Nutr 2006;15:335-340.

15. Coll O, Pisa S, Palacio M, Quinto L, Cararach V. Awareness of the use of folic acid to prevent neural tube defects in a Mediterranean area. Eur J Obstet Gynecol Reprod Biol 2004;115:173-177.

16. Bonin MM, Bretzlaff JA, Therrien SA, Rowe BH. Knowledge of periconceptional folic acid for the prevention of neural tube defects. Arch Fam Med 1998; 7:438-442.

17. Chacko MR, Anding R, Kozinetz C, Grover JL, Smith P. Neural tube defects: knowledge and preconceptional prevention practices in minority young women. Pediatrics 2003;112:536-542.

18. Potzsch S, Hover-Schuschke J, Seelig, M, Steinbicker V. Knowledge among young people about folic acid and its importance during pregnancy: a survey (survey) in the Federal State of Saxony-Anhalt (Germany). J Appl Genet 2006;47:187-190.

19. Secretaría de Salud. Norma oficial mexicana NOM-SSA 2-2002, para la prevención y control de los defectos al nacimiento. Disponible en://www.generoysaludreproductiva.gob.mx/IMG/pdf/norma_nacimiento.pdf.