2003, Number 1
<< Back Next >>
Perinatol Reprod Hum 2003; 17 (1)
Causas de muerte de un grupo de niños con atresia de esófago sometidos a autopsia
Villegas-Álvarez F, González-Zamora JF, Braun-Roth G, López-Corella E
Language: Spanish
References: 33
Page: 28-35
PDF size: 85.87 Kb.
ABSTRACT
Objective: To identify the causes of high mortality in children with esophageal atresia that ingress to the Instituto Nacional de Pediatría by means to study of autopsy data.
Methodology: The source was clinical file date of 87 autopsies in children with the diagnosis of esophageal atresia. Seven variables were studied considered as pronostic factor and they were classified in 2 groups: in the group 1, patients with not corrected surgically and the group 2, patients with surgical correction of the esophageal defect; with these data and the information obtained in material autopsy was determinate the cause of death.
Results: In the group 1, there were 39 patients with not corrected surgically, in this group the cause of the death was determinate in 43% of the cases: the principal causes were multifactorial problems, incompatible with the life malformations and severe prematurity. In the group 2, there were 48 patients operated for the esophageal defect and whose cause of death was etermine d in 60% of the cases. The principal causes of death were identified: Derived complications from the surgical procedure, multifactorial problems and incompatible with the life malformations.
Conclusions: In the cases that the causes of the death could be identified, the principal causes they were: surgical complications and those derived of events that were outside of medical treatment. When it was considered from a multifactorial way, the combination of events were: delay admission to the hospital, associate malformations, initial ventilatory support and the opportunists infections; they were to play a more important paper in the fatal outcome.
REFERENCES
Waterston DJ, Bonham-Carter RE, Aberdeen E. Oesophageal atresia: Tracheoesophageal fistula. A study of survival in 218 infants. Lancet 1962; 1: 819-22.
Holder TM, Claud DT, Lewis JE, Philling GP. Esophageal and tracheoesophageal fistula. A survey of its members by the surgical section of the American Academy of Pediatrics. Pediatrics 1964; 34: 542-9.
Salem MR, Wong AY, Lin YH, et al. Prevention of gastric distension during anesthesia for newborns. Anesthesiology 1973; 38: 82-3.
Louhimo I, Lindah H. Esophageal atresia: Primary results of 500 consecutively treated patients. J Pediatr Surg 1983; 18: 217-29.
Hands LJ, Dudley NE. A comparison between gap-length and Waterston classification as guides to mortality and morbidity after surgery for esophageal atresia. J Pediatr Surg 1986; 21: 404-6.
Delius RE, Wheatley MJ, Coran AG. Etiology and management of respiratory complications alter repair of esophageal atresia with tracheoesophageal fistula. Surgery 1992; 112: 527-32.
Poenaru D, Laberge JM, Neilson IR, Guttman FM. A new prognostic classification for esophageal atresia. Surgery 1993; 113: 426-32.
Rokitansky AM, Kolankaya VA, Seidl S, Mayr J, Bichler B, Scheiner W, et al. Recent evaluation of prognostic risk factors in esophageal atresia- A multicenter review of 223 cases. Eur J Pediatr Surg 1993; 3: 196-201.
Spitz L, Kiely EM, Morecroft JA, Drake DP. Oesophageal atresia: At risk groups for the 1990s. J Pediatr Surg 1994; 29: 723-5.
Agarwala S, Bhatnagar V, Bajpai M, Gupta DK, Mitra DK. Factors contributing to poor results of treatment of esophageal atresia in developing countries. Pediatr Surg Int 1996; 11: 312-15.
Okada A, Usui N, Inoue M, Kawahara H, Esophageal atresia in Osaka: A review of 39 years experience. J Pediatr Surg 1997; 32: 1570-4.
Beasley SW. Influence of associated anomalies on the management of a esophageal atresia. Indian J Pediatr 1996; 63: 743-9.
Saing H, Mya GH, Cheng W. The involvement of two or more systems and the severity of associated anomalies significantly influence mortality in esophageal atresia. J Pediatr Surg 1998; 33: 1596-8.
Choudhury SR, Ashcraft KW, Sharp RJ. Survival of patients with esophageal atresia: Influence of birth weight, cardiac anomaly and late respiratory complications. J Pediatr Surg 1999; 34: 70-4.
Gupta DK, Arora M, Srinivas M. Azygos vein anomaly: The best predictor of a long gap in esophageal atresia and tracheoesophageal fistula. Pediatr Surg Int 2001; 17: 101-3.
Rowe MI, Rowe SA. The last fifty years of neonatal surgical management. Am J Surg 2000; 180: 345-52.
Garci-Nuño AC, Sánchez SG, Cotallo GDC, Martínez AC y col. Atresia de esófago y anomalías asociadas. An Esp Pediatr 1992; 6: 455-9.
Krishna A, Murali MU, Ahuja S, Kaur N. Factors influencing survival in esophageal atresia. Indian Pediatrics 1994; 31: 80-3.
Nawaz A, Matta H, Shawis R, Jazcobsz A. Esophageal atresia and tracheoesophageal fistula: Success and failure rate in the United Arab Emirates. Pediatr Surg Int 1998; 14: 214-7.
Sabbaga C, Schultz C, Garbers JC, Avila SG, doValle MR, Martins IC. Atresia de esófago. Análisis de 89 pacientes. Rev Cir Infant 1997; 7: 81-6.
Driver CP, Shankar KR, Jones MO, et al. Phenotypic presentation and outcome of esophageal atresia in the era the Spitz classification. J Pediatric Surg 2001; 36: 1419-21.
22.Weldt E, Camaño E, Escobar JJ. Atresia esofágica, análisis y seguimiento. Rev Chil Pediatr 1998; 69: 241-6.
González Zamora JF, Villegas-Álvarez F. Atresia de esófago: morboletalidad en el INP, 1971-1999. Acta Pediatr Mex 2001; 22: 411-8.
Muñiz-Escarpanter J, López-Sánchez R. Cortiza-Orbe G, Martínez-García C, Fernández-Bustos P, González-López SL. Atresia esofágica en el recién nacido. Rev Cubana Pediatr 1990; 62: 39-49.
Chittmittrapap S, Spitz L, Kiely EM, Brereton RJ. Anastomotic leakage following surgery for esophageal atresia. J Pediatr Surg 1992; 27: 29-32.
Chittmittrapap S, Spitz L, Kiely EM, Brereton RJ. Anastomotic structure following repair of esophageal atresia. J Pediatr Surg 1990; 25: 508-11.
Montgomery M, Frenckner B. Esophageal atresia: Mortality and complications related to gastroesophageal reflux. Eur J Pediatr Surg 1993; 3: 335-8.
Sharma AK, Shekhawat NS, Agrawal LD, Chaturvedi V, Kothari SK, Goel D. Esophageal atresia and tracheoesophageal fistula: A review of 25 years’ experience. Pediatr Surg Int 2000; 16: 478-82.
Poenaru D, Laberge JM, Neilson IR, Ngoyen LT, Guttman FM. A more than 25-year experience with end-to-end versus end-to-side repair for esophageal atresia. J Pediatr Surg 1991; 26: 472-7.
Spitz L. Esophageal atresia: Past, present, and future. J Pediatr Surg 1996; 31: 19-25.
McKinnon LJ, Kosloske AM. Prediction and prevention of anastomotic complications of esophageal atresia and tracheoesophageal fistula. J Pediatr Surg 1990; 25: 778-81.
Lindahl H, Rintale R, Saviola H. Chronic esophagitis and gastric metaplasia are frequent late complications of esophageal atresia. J Pediatr Surg 1993; 28: 1178-80.
Tovar JA, Diez-Pardo JA, Morcia J, Prieto G, Molina M, Polaned I. Ambulatory 24 -hour manometric and pHmetric evidence of permanent impairment of clearance capacity in pediatric with esophageal atresia. J Pediatr Surg 1995; 30: 1224-31.