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2009, Number 1

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Rev Med Hosp Gen Mex 2009; 72 (1)

Use of amniotic membrane radiosterilized with cobalt-60 for reconstruction of ocular surface

Vázquez-Maya L, Salazar-Escamilla MA, María Esther Martínez-Pardo ME

Language: English
References: 27
Page: 7-15
PDF size: 239.04 Kb.


ABSTRACT

Purpose: To evaluate the efficiency of the Radiosterilized Amniotic Membrane in diseases of the ocular surface, from refractory to conventional treatments. Methods: In this study 17 eyes of 15 patients with corneal ulcer, persistent epithelial defect, alkali burn, symblepharon and the like, were treated with radiosterilized amniotic membrane. 11 men and 4 women were included. They were divided into two groups: in group I there were 10 eyes with epithelial defects and thinning of the stroma, which constituted a menace to the integrity of the eye and seven eyes were used in group II, where it was required to promote an adequate epithelial migration of the eye to avoid exaggerated fibrous scarring after a surgical procedure. Results: The average age of our population was 38.4 ± 22.6, with a range of 12 to 83 years of age. The post surgical follow-up, on average, was 3.1 ± 2.5 months (range of 15 days to 7 months). The desired effect with the membrane was: 90% in group I and 85.7% in group II. Conclusion: The amniotic membrane radiosterilized with cobalt-60 represents an effective and secure treatment for diseases of the ocular surface. This type of membrane has several advantages: low cost, storage at room temperature, translucent, among others.


REFERENCES

  1. Charters L. The factors of growth of the amniotic membrane can be indicating of treatment. Ophthalmology Times: 2001; 28-32.

  2. Azuara-Blanco A, Pillai CT, Dua HS. Amniotic membrane transplantation for ocular surface reconstruction. Br J Ophthalmol 1999; 83: 399-402

  3. Davis JW. Swing transplantation with a review of 550 cases at the Johns Hopkins Hospital. Johns Hopkins Med J 1910; 15: 307.

  4. De Roth A. Plastic repair of conjuntival defects with fetal membranes. Arch Ophthalmol 1940; 23; 522-525.

  5. Sorsby A, Symons HM. Amniotic membrane grafts in caustic burns of the eye (second degree burns). Br J Ophthalmol 1940; 30: 337-345.

  6. Batle JF, Perdomo FJ. Placental membranes as a conjunctival substitute. Ophthalmol 1993; 100-107

  7. Dua HS, Gomes JAP, King AJ et al. The amniotic membrane in ophthalmology. Survey Ophthalmol 2004; 49: 51-77.

  8. Tseng SCG, Prabhasawat P, Barton K et al. Amniotic membrane transplantation with or without limbal allografts for corneal surface reconstruction in patients with limbal stem cell deficiency. Arch Ophtalmol 1998; 116: 431-441.

  9. Salazar EMA, Vázquez ML. Injerto de membrana amniótica para la reconstrucción de la superficie ocular. Poster presented at the XI International Course of Cornea and Refractive Surgery. 2005.

  10. Martínez PME, Reyes FML, Ramos DLE, Gutiérrez SE, Carrera GJ, Marin MA. Clinical application of amniotic membranes on a patient with epidermolysis bullosa. Ann Transplant 1999; 4 (3-4): 68-73.

  11. Martínez PME, Reyes FML. The tissue bank at the National Nuclear Research Institute in Mexico. Cell and Tissue Banking 2003; 4: 163-168.

  12. Ley CE, Martínez PME, Román R, Oliveros LF, Canchola ME. Application of biological dressings from radiosterilized amnions with Cobalt 60 and serologic studies on the handling of burns in pediatric patients. Ann Transplant 2003; 8 (4): 46-49.

  13. Martínez PME, Ley CE, Reyes FML, Rodríguez FP, Vázquez ML, Salazar EMA. Radiat Phys Chem 2007; 76/11-12, 1771-1774.

  14. Shimazaki J, Shinozaki N, Tsubota K. Transplantation of amniotic membrane and limbal autograph for patients with recurrent pterygium associated with Symblepharon. Br J Ophthalmol 1988; 82: 235-240.

  15. Prado-Serrano A. Alteraciones corneales en un caso de epidermólisis bulosa. Rev Mex Oftalmol 2003; 4: 153-156.

  16. Chen HJ, Pires RTF, Tseng SCG. Amniotic membrane transplantation for severe neurotrophic corneal ulcers. Br J Ophthalmol 2000; 826-833.

  17. International Atomic Energy Agency 2002; International Standards for Tissue Banks, Vienna.

  18. International Organization for Standardization (ISO) Sterilization of health care products-radiation sterilization-substantiation of 25 kGy as a sterilization dose for small or infrequent production batches, 1996; ISO 13409, Geneva.

  19. Martínez-Pardo ME, Mariano-Magaña D. The tissue bank at the Instituto Nacional de Investigaciones Nucleares: ISO 9001:2000 certification of its quality management system Cell and Tissue Banking 2006; 8: 221-231.

  20. Siennicka A, Pecold-Stepniewska. Transplantation of amniotic membrane for patients with bullous keratopathy and chemical and thermal burns. Klin Oczna 2003; 105 (1-2): 41-45.

  21. Dua HS. Amniotic membrane transplantation. Br J Ophthalmol 1999; 83: 748-752.

  22. Madhavan HN. Preparation of amniotic membrane for ocular surface reconstruction. Indian J Ophthalmol 2002; 50 (3): 227-231

  23. Adds PJ. Bacterial contamination of amniotic membrane. Br J Ophthalmol 2001; 85: 228-230.

  24. Barabino S. Role of amniotic membrane transplantation for conjuntival reconstruction in ocular-cicatricial pemphigoid. Ophthalmology. 2003; 110(3):474-80

  25. Khokar S. Amniotic membrane transplantation in refractory neurotrophic corneal ulcers: A randomized, controlled clinical trial. Cornea. 2005; 24 (6): 654-660.

  26. Tosi GM. Amniotic membrane transplantation in ocular surface disorders. J Cell Physiol 2005; 202: 849-851.

  27. Singh R. Properties of air dried processed amniotic membranes under different storage conditions. Cell Tissue Banking 2003; 4: 95-100.




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