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Boletín Médico del Hospital Infantil de México

2009, Number 2

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Bol Med Hosp Infant Mex 2009; 66 (2)

Asthma, obesity and gastroesophageal reflux disease association in children

Villalpando-Carrión S, Ura-Hernández JP, Río-Navarro BE, Heller-Rouassant S

Language: Spanish
References: 29
Page: 153-159
PDF size: 139.55 Kb.


ABSTRACT

Introduction. Gastroesophageal reflux disease (GERD) is highly prevalent in México. GERD may appear as a symptom of asthma, and has been widely associated with obesity; asthma and obesity are also associated. The aim of this study was to determine the frequency of GERD symptoms in obese patients with or without asthma.
Methods. This is a longitudinal study in which GERD symptoms were evaluated according to a validated questionnaire in obese patients with or without asthma.
Results. Seventy-five patients with an average age of 11.9 ± 2 years were included. Their mean BMI was 26.7 ± 4 kg/m2 (BMIz score 3.8 ± 1.7). We found GERD symptoms in 36 patients (48%). Fifty-two percent of the patients also had a diagnosis of asthma; 27 (36%) asthmatic patients showed GERD symptoms and asthma, and only 9 patients (12%) without asthma had GERD symptoms. This is a significant difference (χ2 =14.6, P ‹0.05). The odds ratio of having GERD symptoms for obese patients with asthma was 6.75 (IC 95% 2.4-18.6).
Conclusion. Asthma and obesity on a concurrent basis increase considerably the risk of developing GERD symptoms in children. Management of patients with simultaneous obesity and asthma is as an important challenge for practitioners. New clinical guidelines for a better approach to obese children are needed in view of the imminent epidemiological transition in our country.


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