Márquez GVJ, Athie GJM, Martínez RV, Báez R

Language: Spanish
References: 25
Page: 5-12
PDF size: 81.51 Kb.

ABSTRACT

Objective: To calculate changes in blood pressure and cardiac frequency during laryngoscopy and orotracheal intubation in patients submitted to general anesthesia with remifentanyl and fentanyl. Methodology: A non-randomized clinical study was conducted. Blood pressure (BP) and cardiac frequency (CF) were recorded after induction of anesthesia and 1 min after performing laryngoscopy and intubation. Patients received a bolus injection of remifentanyl 1 µg/kg (Group R) 3 min prior to laryngoscopy followed by an infusion of 0.200 µg/kg/min (5 ng/mL plasma concentration). Patients of the fentanyl group (Group F) received an initial bolus injection of 2 µg/kg 3 min prior to laryngoscopy. All patients were induced with propofol 1.5 mg/kg. For neuromuscular relaxation, we utilized rocuronium bromide 0.3 mg/g. Laryngoscopy was performed by means of the customary technique. The changes demonstrated by fentanyl during induction were fewer than those observed in Group R patients. Mean blood pressure (MBP) in both groups was maintained at safe limits to ensure organic perfusion. Conclusion: Fentanyl showed greater stability at the moment of induction and of intubation, with fewer variations in hemodynamic variables (systolic blood pressure [SBP], diastolic blood pressure [DBP], and MBP). Nonetheless, fentanil presented a greater increase in CF at the moment of intubation with respect to remifentanyl.

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