2004, Number 2
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Rev Med Inst Mex Seguro Soc 2004; 42 (2)
Clinical-Surgical Practice in Stage II Cerebral Astrocytomas
Sandoval BM, Rangel MC, Castillo HJ, Becerra LM, Sandoval OL
Language: Spanish
References: 22
Page: 157-162
PDF size: 129.43 Kb.
ABSTRACT
Introduction: gliomas are primary neoplasia of the central nervous system. These are tumors of neuroepithelial origin, and represent up to 22 % of surgery for neoplasia in our Department. This study relates the experience of the Department in management of these neoplasia.
Materials and methods: this is a retrospective study. We studied all patients with stage II astrocytoma (WHO classification). We included 16 patients with control for 3 years during the period from January 1, 1994-December 31, 2000.
Results: patients with stage II astrocytoma repre-sented up to 19 % of all gliomas. Patients had evolution to 38 months, and principal symptoma-tology included seizures in 66 %. We carried out total resection in 82%. Histologic type variety was diffuse fibrillary astrocytoma in 46 %; 93 % of patients received radiotherapy postoperatively. There were no deaths during the period analyzed.
Conclusions: total resection of the tumor and radiotherapy postoperatively are useful in man-agement of patients with stage II brain astro-cytoma according to the WHO classification.
REFERENCES
1. Russell DS, Rubinstein LJ. Pathology of tumors sys-tem. Fifth edition. London: Edward Arnold; 1989.
2. World Health Organization. Classification of tumors. En: Kleihues P, Cavenee WK, editors. Pathology and genetics tumors of the nervous system. Lyon: Inter-national Agency for Research on Cancer (IARC) Press; 2000. p. 6-7.
3. Preston MS. Epidemiology. En: Berger W, editor. The gliomas. Philadelphia: WB Saunders Company; 1999.
4. McCormack BM, Budzil GN, Voorhees JC, Ransohoff J. Treatment and survival of low astrocytoma in adults 1977-1988. Neurosurgery 1992;31:636-642.
5. Lunssford LD, Somozaa S, Kondzziolka D, Flickinger JC. Brain astrocytomas: biopsy, the irradiation. Clin Neurosurg 1995;42:464-479.
6. Lunsford LD, Niranjan A. The rational surgery for fibrillary astrocytomas. San Antonio, Texas; Lippin-cott-Williams and Wilkins; 2000.
7. Gehan EA, Walker MD. Prognostic factors for patients with brain tumors. Monogr Natl Cancer Inst 1977;61: 295-301.
8. Van Veelen MLC, Avezaat CJJ, Kros JM, van Putten W. Supratentorial low-grade astrocytoma: prognostic factors, differentiation, and the issue of early versus late surgery. J Neurol Neurosurg Psychiatry 1998;64: 581-587.
9. Byrne T, Piepmeier J, Yoshida D. Imaging and clinical features of gliomas. En: Tindal G, Cooper P, editors. The practice of neurosurgery. Baltimore: Williams and Wilkins; 1995. p. 637-648.
Konndziolka D, Lunsford D, Martínez J. Unreliability of comtemporary neurodiagnostic imaging in eva-luation suspected adult supratentorial (low grade) astrocytoma. J Neurosurg 1993;79:533-537.
Lam WW, Chan KW, Wong WL, Poon WS, Metreweli C. Institution Department of Diagnostic Radiology and Organ Imaging, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong SAR, China. Preoperative grading of intracranial glioma. Source Acta Radiol 2001;42(6):548-554.
Morales OE, Sandoval BM. Bloqueos tronculares con propofol-fentanil en infusión para craneotomías con paciente despierto. Educación e Investigación Clínicas 2000;(1);44.
Jackson RJ, Fuller GN, Abi-Said D. Limitations of stereotactic biopsy in initial management of gliomas. J Neurooncol 2001;60(6):804-808.
Laws ER, Shaaffrey ME. Surgical management of intracranial gliomas: biopsy, resection for watchful waiting. San Antonio, Texas: Lippincott-Williams and Wilkins; 2002. p. 37-45.
Nazzaro JM, Neuwelt EA. The role of surgery in the management of supratentorial intermediate and high-grade astrocytoma in adults. J Neurosurg 1990;73:331-344.
Peeeraud A, Meschede M, Ilmberrger J, Reulen HJ. Surgical resection of grade II astrocytomas in the superior frontal gyrus. Neurosurgery 2002;50:946-967.
Trautmann TG, Shaw EG. Supratentorial low-grade gliomas: Is therapeutic role of radiation therapy? Ann Academic Med Singapure 1996;25:392-396.
Schimidt MH, Bergeer MS, Katheleen RL, Aldape K, Dermott W, Oprados MD, Chang SM. Repeated operations for filtrative low gliomas without inter-vening therapy. J Neurosurg 2003;98:1165-1169.
Shaww EG. The low-grade glioma debate: evidence defending the position of early radiation therapy. Neurosurgery 1995;42:488-494.
Akyol FH, Athan IL, Zorlu F, Gurkaaynak M, Alanyali H, Ozzyar E. Results of postoperative or exclusive radiotherapy in grade I and II cerebelar astrocytomas patients. Radiother Oncol 1992;23:245-248.
Title false-negative Tc-99m MIBI scintigraphy in histopathologically proved recurrent high-grade oligodendroglioma. Source Clin Nuclear Med 2003;28(4):299-301.
Schmidt D, Gottwald U, Langen KJ, Weber F, Hertel A, Floeth F, Felsberg J, Reifenberger G, Coenen HH, Muller-Gartner HW. Institution Clinic of Nuclear Medicine, Heinrich-Heine-University Dusseldorf, Germany. Title 3-[123I]Iodo-alpha-methyl-L-tyrosine uptake in cerebral gliomas: relationship to histological grading and prognosis. Source European Journal of Nuclear Medicine 2001;28(7):855-61.