2009, Number 1
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Med Sur 2009; 16 (1)
Procalcitonin in cardiac surgery, what is its current value?
De Anda JMC, Herrera GJC, Cárdenas AA, Morales ED, López GS, González-Chon O
Language: Spanish
References: 16
Page: 19-24
PDF size: 92.15 Kb.
ABSTRACT
Procalcitonin – a prohormone derived from Thyroid C cells – has been a useful marker in systemic inflammatory states, infectious and septic conditions during the last decade. There are several clinical studies that support its utility in such conditions, but when it comes to cardiac surgery only a scarce number of reports exist. The diagnosis of infection after cardiac surgery is not easy; there is lack of a 100% either sensitive or specific marker for such purposes. The surgical intervention herself produces a systemic inflammatory response syndrome and thus elevation of inflammation markers such as C reactive protein and procalctitonin in the absence of an infectious process. Elevated procalcitonin levels in the context of cardiac surgery nowadays should be translated with caution.
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