2008, Number 38
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Med Univer 2008; 10 (38)
Prevalence of cholelithiasis in pediatric patients
Ferrándiz MCA, de la O CME, Cura EIA, Montes TFF, Zapata CCA
Language: Spanish
References: 18
Page: 22-28
PDF size: 269.32 Kb.
ABSTRACT
Background: Until a few years ago, biliary lithiasis during childhood was considered an infrequent disease that was fundamentally associated to hemolytic disease.
Objective: determine the prevalence of cholecystolithiasis and associated factors in pediatric patients.
Materials and Methods: An observational cross-sectional, retrospective and comparative study in patients that were admitted to the Pediatric Service of the Dr. Jose Eleuterio González University Hospital from 2002 to 2006 with a diagnosis of cholecystolithiasis confirmed by ultrasound.
Results: The prevalance of cholecystolithiasis was 0.35%. That study included 42 patients (37 female, 5 male) with an average age of 13 years; the most frequent localization of pain was in the right hypochondrium (69.8%). Laboratory tests reported leukocytosis in 14% and liver tests were abnormal in 35%, elevated cholesterol in 24%, and elevated serum amylase in 6 patients. The associated factors found were: female 88%, adolescence 86%, obesity 43%, overweight 29%, hypercholesterolemia 24%, pregnancy 23%, ceftriaxone 5%, TPN 5%, Down Syndrome 2%, oral contraceptives 2%, Crohn´s disease 2%, hemolysis 2% and a positive family history in 4 patients. Management was surgical in 100% of cases, of which 81% were performed by laparoscopy, with complications in 19% of the patients.
Conclusions: The prevalence of cholecystolithiasis shows an increase in the last 5 years at the University Hospital, mainly in females and in adolescents, with the main associated factors being obesity, overweight, hypercholesterolemia and gestation.
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