2008, Number 4
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Acta Med 2008; 6 (4)
Brucellosis. A current infection
Vega LCA, Ariza AR, Rodríguez WFL
Language: Spanish
References: 33
Page: 158-165
PDF size: 85.58 Kb.
ABSTRACT
Brucellosis is a zoonosis due to genus
Brucella which is a negative gram bacillus. It was identified for the first time in the Mexican Republic in 1905 and since then it has been a permanent entity. The
Brucellas are classified in six species of which only
B. melitensis, B. abortus, B. suis, and
B. canis infects the man. The main causes of infection are through the ingestion of unpasteurized milk and by the contact with infected animals. The lipopolysaccharide that is in the membrane of the bacterium it is the major determinant of virulence. The clinical manifestations are non-specific and the brucella can produce located forms in a 30% of the cases. The diagnosis is based on the isolation of the microorganism in cultures of blood and other weaves. Serologically we have some methods like the agglutination in tube and the polymerase chain reaction. The treatment recommended by the World Health Organization is according to three schemes and the best treatment is with aminoglycosides and tetracyclines. The main cause of mortality is endocarditis and meningoencephalitis. The prevention includes principally avoiding the contact with infected animals and the pasteurization of milky products.
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