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2008, Number 4

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Rev Mex Anest 2008; 31 (4)

Peridural dexmedetomidine in local anesthesia in order to decrease anxiety

Oriol-López SA, Maldonado-Sánchez KA, Hernández-Bernal CE, Castelazo- Arredondo JA, Moctezuma RL

Language: Spanish
References: 15
Page: 271-277
PDF size: 64.30 Kb.


ABSTRACT

The use of adjuvants in local anesthesia in order to decrease the anxiety is frequently associated to deep sedation, and a consequent respiratory depression. The emergence of alpha 2 agonists, important because of their qualities (sedation, analgesia and amnesia), allows their use by intravenous via during anesthesia. Finding their receptors at the medullar level will give diverse sedation levels when administering them by epidural via, improving anesthesia’s quality and decreasing the use of adjuvant intravenous drugs. Results: 40 (female and male) patients were included in this study. They were subjected to abdominal and lower members surgery. They were given epidural dexmedetomidine at a dose of 1 µg/kg, plus lidocaine and epinephrine at 3-4 mg/kg. The obtained sedation degree, according to Ramsay, at five minutes was of 3, and it was of 3-4 from 15 to 90 minutes, in the 90% of the population. These frequencies were analyzed through the χ2, being p ‹ 0.05. The patients kept their hemodynamic parameters stable, without respiratory depression.


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