2005, Number 2
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Med Crit 2005; 19 (2)
New therapeutic options for the postraumatic hemorrhage
Carrillo ER, Cedillo THI
Language: Spanish
References: 37
Page: 60-70
PDF size: 110.78 Kb.
ABSTRACT
Hemorrhage is one of the most common contributors to mortality in trauma patients. In the 50’s the American College of Surgeons recommended surgical control and aggressive reanimation in those patients; this therapeutic modalities were based in experimental models developed at that time. The primary end-points suggested included: substitution of circulating blood volume with a relation 3:1 and the maintenance of blood pressure in normal values without considering hemorrhage control. Nevertheless, recent clinical evidence and new experimental models have brought out that those therapeutics modalities, including elevation of blood pressure previous to hemorrhage control, are deleterious, and actually increase mortality in this population. These observations contributed to development of permissive, deliberated and delayed hypotension as new alternatives in treatment of trauma patients with hemorrhage. The objective of this study is to review actual concepts in the management of hemorrhage in trauma patients.
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