2004, Number 1-2
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Plasticidad y Restauración Neurológica 2004; 3 (1-2)
Alzheimer’s disease. Clinical, diagnosis and neuropathology studies
Proaño NJ, Aguilar RF
Language: Spanish
References: 20
Page: 95-105
PDF size: 188.38 Kb.
ABSTRACT
Increase of word population average life span is accompanied by increment of against associated pathology.
The dementia is clinically characterized by alterations of cognition memory problems in short term memory, orientation, calculation and judgment, etc, progressive and association with motor control, behavior and personality changes. Diagnosis include neurological evaluation motor, cognition and laboratory.
Fortunately, technological advances allow early diagnosis through non-invasive, Neuroimaging methods. Morphological and functional information of the normal or pathological brain is obtainer. These data are useful in diagnosing several types of dementia (Alzheimer’s vascular, fronto-temporal, AIDS, dementia complex, etc.). “Treatable causes of dementia” are detected with these procedures, such as chronic subdural hematoma, normal pressure hydrocephalus, depression, primary tumors and brain metastatic illness. Functional images offer neurochemical information about certain brain metabolites, which are helpful in differential diagnosis of several others CNS illnesses with signs or symptoms similar to dementia. Neurophatological studies are de gold standard to observe neurofibrilary tangles and amiloid plaques.
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