Carrillo GJE, Sánchez IDA, Cano RC, Rotberg JT

Language: Spanish
References: 22
Page: 379-384
PDF size: 159.29 Kb.

ABSTRACT

Background: Microalbuminuria is defined as the presence of low urine albumin levels and is a clinical expression of endotelial damage, it has a strong association with cardiovascular mortality and during an acute coronary syndrome it has prognostic correlationship.
Objetive: To measure semiquantitative microalbuminuria to establish the relationship between coronary affection and the correlation with reactive C protein levels.
Methods: We included patients who were admitted to the emergency room with an acute coronary syndrome(SICA), and a diagnostictherapeutic coronariography was made. Microalbumin levels were determined using reactive strips at their arrival to the ER and the levels were correlated to the angiographic findings such as stenosis or atheromathosis and to levels of PCR.
Results: 37 patients, 27 (72.9%) had microalbuminuria and 10 (27.02%) not. The average age was 55.9 ± 13 years and 65.5 ± 17 years in each group. The characteristics of the population were: hypertension (48.1 vs 14.81%, p = 0.474), smoking (59.26 vs 18.52%, p = 0.445), diabetes (25.93 vs 3.7%, p = 0.288), creatinin (1.04 ± 0.45 vs 1.12 ± 0.25, p = 0.584), cholesterol (198 vs 180 mg/dL, p = 0.838), tryglicerides (159 vs 150 mg/dL, p = 0.95), LDL (103.09 ± 46.26 vs 110.09 ± 33.12 mg/dL, p = 0.645), HDL (45.38 ± 16.09 vs 38 ± 16.09 mg/dL, p = 0.218), PCR (0.72 vs 0.52 mg/L, p = 0.255). The levels of microalbuminuria correlated with the atheromatosis degree, r = 0.50 (p = 0.001) and with the coronary occlusion (r = 0.489, p = 0.002). Microalbuminuria didn’t correlate with PCR (r = 0.001, p = 0.888).
Conclusions: Measured by a semiquantitative method, microalbuminuria correlates with the degree of atheromatosis and coronary stenosis in a SICA. PCR didn’t correlated with microalbuminuria.

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