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Boletín Clínico de la Asociación Médica del Hospital Infantil del Estado de Sonora

2007, Number 1

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Bol Clin Hosp Infant Edo Son 2007; 24 (1)

Cryptorchidism: The Importance of Early Diagnosis.

López-Cruz G, Pérez-Campos E, Hernández-Cruz P

Language: Spanish
References: 52
Page: 32-37
PDF size: 179.66 Kb.


ABSTRACT

Introduction. Crytorchidism includes the absence of palpable testicle, the incapacity to make it descend to scrotum manually and also when, once descended by means of suitable maneuvers, it returns immediately to its previous position outside scrotum. The diagnosis of crytorchidism; it must be made at birth. The delay in the diagnosis is associated to two main consequences: Infertility and testicular cancer. The infertility; it is the consequence commonest of crytorchidism, one appears in 10% in unilateral cases and 38% in bilateral. The changes documented in patients with infertility include: Degenerative diminution of the tubular diameter, changes in the germinal cells and sertoli and cells, death of germinal cells by increase of the fetal temperature and “gonadal dysgenesis”. The testicular cancer; it is a less frequent disease. In countries nevertheless industrialized it has increased his incidence, mainly in young adolescents and adults. The factors associated to cancer are: Crytorchidism, subfertility, abnormalities in semen, “testicular dysgenesis”, embryologic remnants, remnants of Müller, genetics (mutations in the genes of the androgen receivers, chromosome 12) and cellular apoptosis. Conclusión. The diagnosis of crytorchidism must be made at the time of the birth, to grant the opportune treatment, and to avoid the long term complications like the infertility and cancer.


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