medigraphic.com
Instituto Nacional de Neurología y Neurocirugía

2007, Number 1

<< Back Next >>

Arch Neurocien 2007; 12 (1)

Neuropsychological evaluation pre and post surgery in patients with frontal tumors

Rojas RSI, Lorenzana GRD, Luviano L, Yánez G, Ruiz GE, Hernández GL

Language: Spanish
References: 18
Page: 14-24
PDF size: 202.08 Kb.


ABSTRACT

Frontal tumors represent 16% of all supratentorial neoplasm. They can be present at the same rate in both hemispheres. The symptoms are easily confused as psychiatrics instead of neurological. Meningiomas and astrocitomas (glyomas) show high incidence, some studies have shown 90% of patients who have a frontal tumor, have a deficit in the execution in neuropsychological tests, below percentil 10 according to their group in any of the cognition areas.Executive deficit functions were observed in 78% of patients, while memory and attention deficits were observed in 60%. Objetive: cognitive function deficit evaluation and the executive functions alteration rank pre and post surgery in patients with frontal tumors. Methods: there were evaluated 4 patients, 3 women and 1 man between 47-69 years old who had frontal tumors (Meningyoma and astrocitoma). It was used a general trail test for cognitive functions (PIEN), one specific test to evaluate executive functions (WCST) and one scale to identify anxiety and depression grade (EADH). Results: the presurgycal evaluation of all patients showed memory, attention and oral fluency deficits. The obtained scores in the test for executive functions play all of them below percentil 1. The executive functions more affected in this kind of patients are: incompetency to classify, perseverancies and no profit from verbal feed-back. Conclusion: the cognositive function deficit is not a early symptom caused by frontal tumors. Surgery of this tumors do not improve impair general cognition. Patients with meningyomas, who went under surgery, had a better prognosis about cognitive functions.


REFERENCES

  1. Afifi A, Bergman R. Neuroanatomía funcional. (2ª ed.). México D. F. McGraw Hill. 2006.

  2. Stuss D, Alexander M, Floden D, Binns M, Levine B, Mcintosh A, et al. Fractionation and localization of distinct frontal lobe process: evidence from focal lesions in humans. En Stuss D Knight R. (Eds.) Principles of frontal lobe function. Nueva York, NY, EE. UU.: Oxford University Press. 2002.

  3. Tirapu J, Muñoz J, Pelegrín C. Funciones ejecutivas: necesidad de una integración conceptual. Rev Neurol 2002;34:(7)673-85.

  4. Tirapu J, Muñoz J, Pelegrín C, Albéniz A. Propuesta de un protocolo para la evaluación de las funciones ejecutivas. Rev Neurol 2005; 41(3):177-86.

  5. Gudin M. Cerebro y afectividad. Pamplona, España. 2001.

  6. Fuster J. The prefrontal cortex. (2ª ed.). Nueva York, NY, EE. UU. Reven Press 1989.

  7. Anderson V, Levin H, Jacobs R. Executive Functions alter Frontal Lobe Injury: a developmental perspective. En stuss D, knight R. Eds. Principles of frontal lobe function. Nueva York, NY, EE. UU. Oxford University Press. 2002.

  8. Luria AR. Las funciones corticales superiores en el hombre (Vol. II). Barcelona, España. 1983.

  9. Nakawatase T. Frontal lobe tumors. En Miller B. Cummings L. The human frontal lobes. Nueva York, NY, EE. UU. The Guilford Press. 1999.

  10. Pérez L, Galárraga J, Gómez H, Tamayo JD. Clasificación de los gliomas astrocíticos. Breves consideraciones. Rev Neurol 2001; 31:(12)1180-3.

  11. González F, Gorina N, Delgado M, Novo R, Chaveco D. Meningiomas: estudio de cinco años. Recuperado el 28 de mayo del 2006 del sitio web http:www.monografias.com 2005.

  12. Glen HJ, Stevens DO. Brain Tumor. Recuperado el 28 de mayo del 2006 del sitio web del The Cleveland Clinic: http:www.clevelandclinic.org/neurosurgery/braintumor/ 2003.

  13. Tucha O, Smely C, Lange K. Effects of surgery on cognitive functioning of elderly patients with intracranial meningioma. Brain J Neurosurg 2001; 15(2):184-8.

  14. Tucha O, Smely C, Preier M, Becker G, Paul M, Lange K. Preoperative and postoperative cognitive functioning in patients with frontal meningiomas. J Neurosurg 2003; 98 (1), 21-31.

  15. Tucha O, Smely C, Preier M, Lange KW. Cognitive deficits before treatment among patients with brain tumors. Neurosurgery 2000; 47(2), 324-33.

  16. Peña CJ. Programa integrado de exploración neuropsicológica “test de Barcelona”. Barcelona, España: Masson, S. A. 1990.

  17. Heaton RK, Chelune GJ, Talley JL, Kay GG, Curtiss G. Test de clasificación de tarjetas de Wisconsin (L. M. Cruz, Trad.). Madrid, España: TEA. 1997.

  18. Zigmong AS, Snaith RP. The hospital anxiety and depression scale. Acta Psychiatry Scand 1983;67:361-79.




2020     |     www.medigraphic.com