Carrillo ER, Ramírez RF, Castro F, Carrillo CLD

Language: Spanish
References: 17
Page: 196-199
PDF size: 93.36 Kb.

ABSTRACT

Dupuytren´s disease causes disability because of the development of finger flexion deformities, with distinct nodule and cord formation on palmar fascia. This results in physical shortening of the diseased fascial tissue through a combination of cell-mediated contraction and matrix remodeling secondary to fibrogenic cytokines. Dupuytren fibroblasts, particularly nodule miofibroblasts, exhibited increase force generation and a delay in reaching tensional homeostasis. This is the fundamental processes involved in the pathogenesis and progression of clinical flexion deformities. We present images characteristics of Dupuytren´s disease.

REFERENCES

1. Elliot D. The early history of Dupuytren´s Disease. Hand Clin 1999; 15: 1-19.

2. Dupuytren G. De la retraction des doigts par suite d´une affection de l´aponevrose palmaire-description de la maladie-operation Chirugicale qui convient dens cas. J Univ Hebd Med Chir Prat Inst Med 1831; 5: 349-365.

3. Ross DC. Epidemiology of Dupuytren´s disease. Hand Clin 1999; 15: 53-62.

4. Ling RS. The genetic factor in Dupuytren´s disease. J Bone Joint Surg Br 1963; 45: 709-718.

5. Arkkita PE, Kantola IM, Viikari JS. Dupuytren´s disease: association with chronic diabetic complications. J Rheumatol 1997; 24: 153-159.

6. Burge P, Hoy G, Regan P, Milne R. Smoking, alcohol and the risk of Dupuytren´s contracture. J Bone Joint Surg Br 1997; 79: 206-210.

7. Noble J, Arafa M, Royle SG, McGeorge G, Crank S. The association between alcohol, hepatic pathology and Dupuytren´s disease. J Hand Surg 1992; 17: 71-74.

8. Magro G, Fraggeta F, Colombatti A, Lanzafame S. Myofibroblasts and extracellular matrix glycoproteins in palmar fibromatosis. Gen Diagn Pathol 1997; 142: 185-190.

9. Badalamente MA, Hurst LC. The biochemistry of Dupuytren´s disease. Hand Clin 1999; 15: 35-42.

10. Tomasek JJ, Gabbiani G, Hinz B, Chapponier C, Brown RA. Myofibroblasts and mechano-regulation of connective tissue remodeling. Nat Rev Moll Cell Biol 2002; 3: 349-363.

11. Gabbiani G, Majno G. Dupuytren´s contracture: fibroblast contraction? An ultrastructural study. Am J Pathol 1972; 66: 131-146.

12. Bayat A, Watson JS, Stanley JK, Ferguson MW, Ollier WE. Genetic susceptibility to Dupuytren disease: association of Zf19 transcription factor gene. Plast Reconstr Surg 2003; 111: 2133-2139.

13. Rayan GM. Dupuytren disease: Anatomy, pathology, presentation, and treatment. J Bone Joint Surg 2007; 89.

14. Rayan GM. Clinical presentation and types of Dupuytren´s disease. Hand Clin 1999; 15: 87-96.

15. Rayan GM, Moore J. Non-Dupuytren´s disease of the palmar fascia. J Hand Surg 2005; 30: 551-556.

16. Wheeler ES, Meals RA. Dupuytren´s diathesis: a broad spectrum disease. Plast Reconstr Surg 1981; 68: 781-783.

17. Schneider LH, Hankin FM, Eisenberg T. Surgery of Dupuytren¨s disease: a review of the open palm method. J Hand Surg 1986; 11: 23-27.