2005, Number 1
Acute lymphoblastic leukemia. A clinical case
Language: Spanish
References: 6
Page: 44-46
PDF size: 37.57 Kb.
ABSTRACT
This 23 year-old female was admitted to the hospital because of abdominal pain, nausea, vomiting, dyspnea, fever and sweating; she had lost 20 kg in a two-year period. On physical examination lymph node enlargements were found as well as liver and spleen enlargements. The CBC disclosed pancytopenia: Anemia of 8.6 g/dl, leukopenia of 1,700 and thrombocytopenia of 64,000. The bone marrow aspirate study showed heavy infiltration by lymphoblasts exhibiting the antigens CD10, CD19 and CD20, consonant with B-cell line acute lymphoblastic leukemia. The patient was treated with combined chemotherapy which included vincristine, asparaginase, mitoxantrone and dexametasone; she has had an initial good response.REFERENCES
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Ruiz-Argüelles GJ, Garcés-Eisele J, Reyes-Núñez V, Pérez-Romano B, Ruiz-Argüelles A, Ramírez-Cisneros F, López-Martínez B, López-Tapia JD, Rivadeneyra-Espinoza L. Assessment of residual disease in acute leukemia by means of polymerase chain reaction: A prospective study in a single institution. Rev Invest Clin Mex 2000; 52: 118-124.
Gómez-Almaguer D, Montemayor J, González-Llano O, Ruiz-Argüelles GJ, Betz NL, Marfil-Rivera J. Leukemia and nutrition IV. Improvement in the nutritional status of children with standard-risk acute lymphoblastic leukemia is associated with a better tolerance of continuation chemotherapy. Int J Ped Hematol/Oncol 1995; 2: 53-56.