2007, Number 3
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Rev Mex Oftalmol 2007; 81 (3)
Estudio piloto de cirugía combinada de facoemulsificación y vitrectomía calibre 25 asistida con triamcinolona y bevacizumab en pacientes con catarata y edema macular diabético difuso
Hernández-Da Mota SE, Chacón-Lara A, Hernández-Vázquez E
Language: Spanish
References: 26
Page: 152-157
PDF size: 100.93 Kb.
ABSTRACT
Purpose: To evaluate the safety and efficacy of combined phacoemulsification and triamcinolone assisted vitrectomy with application of bevacizumab in patients with cataract and diffuse diabetic macular edema.
Methods: In this prospective, non-randomized, interventional case series we included 13 eyes of 13 patients with subcapsular cataract and diffuse macular edema and they underwent phacoemulsification, 25G triamcinolone assisted vitrectomy, endophotocoagulation and bevacizumab injection at the end of the procedure. We performed a follow-up with basal best corrected visual acuity, fluorescein angiography, optical coherent tomography at two weeks, one, three and six months of having performed the procedure.
Results: An improvement in best-corrected visual acuity of at least two lines was seen in 11 patients. The basal average central macular thickness was 358.23 µ (SD 50 µ) while at the end of follow-up it was of 216.6 µ (SD 23.2 µ).
Conclusion: This combined surgical and pharmacological treatment in the six-month period of follow-up resulted in an improvement of central macular thickness and non-progression of diabetic retinopathy. Larger, comparative series are mandatory to establish the real efficacy of this treatment approach.
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