Pizarro-Barrera ME, Garza-León MA, Beltrán-Díaz de la Vega F, Naranjo-Tackman R

Language: Spanish
References: 15
Page: 148-151
PDF size: 40.56 Kb.

ABSTRACT

Objective: To evaluate the corneal endothelium density according to the number of evaluated cells and to find the most constant number of cells.
Methods: Prospective transverse and observational study. Non-contact specular microscopies were realized, counting 20, 30, 40, 50 and 70 cells. The data were analyzed to find the number of cells closer to the average and the variability of the results.
Results: Thirty specular microscopies were evaluated, from healthy volunteers. 66% male, with an average age of 28.3 ± 13.72 (range of 17-84). The average of endothelial cells in the group of 20 cells was 2541.66 ± 451.64 cells/mm², in the 30 cells group was 2552.70 ± 431.12, in the 40 cells group was 2439.53 ± 417.36, in the 50 cells group was 2542.16 ± 97.46 and in the 70 cells group it was 2569.60 ± 361.72. The general average was 2549.26 ± 407.29. There was no significant statistical difference between the groups.
Conclusions: In this group of healthy patients, there’s a high reproducibility in all endothelial cell counts and there’s no difference between the number of cells studied.

REFERENCES

1. Stocker FW. The endothelium of the cornea and its clinical implications. Trans Am Ophthalmol Soc 1953; 51:669-78.

2. Mishima S. Clinical investigations on the corneal endothelium. Ophthalmology 1982; 89:525-30.

3. Waring GO 3rd, Bourne WM, Edelhauser HF, Kenyon KR. The corneal endothelium: normal and pathologic structure and function. Ophthalmology 1982; 89:531-90.

4. Nasser-Hashemian M, Moghiami S, Aghsaide Fard M y cols. Corneal endothelial cell density and morphology in normal Iranian eyes. BMC Ophtalmology 2006; 6:9-14.

5. Bourne WM, Nelson LR, Hodge DO. Continued endothelial cell loss ten years after lens implantation. Ophthalmology 1994, 101:1014-22.

6. Walkow T, Anders N, Klebe S. Endothelial cell loss after phacoemulsification: relation to preoperative and intraoperative parameters. J Cataract Refract Surg 2000; 26:727-32.

7. Pop M, Payette Y. Initial results of endothelial cell counts after Artisan lens for phakic eyes. Ophthalmology 2004; 111:309-17.

8. Landesz M, Siertsema JV, Van Rij G. Comparative study of three semiautomated specular microscopes. J Cataract Refract Surg 1995; 21:409-16.

9. Ohno K, Nelson LR, McLaren JW y cols. Comparison of recording systems and analysis methods in specular microscopy. Cornea 1999; 18:416–423.

10. Benetz BA, Diaconu E, Bowlin SJ y cols. Comparison of corneal endothelial image analysis by Konan SP8000 noncontact and Bio-Optics Bambi Systems. Cornea 1999; 18:67–72.

11. Snellingen T, Rao GN, Shrestha JK y cols. Quantitative and morphological characteristics of the human corneal endothelium in relation to age, gender, and ethnicity in cataract populations of South Asia. Cornea 2001; 20:55–58.

12. Matsuda M, Yee RW, Edelhauser HF. Comparison of the corneal endothelium in an American and a Japanese population. Arch Ophthalmol 1985; 103:68–70.

13. Padilla MD, Sibayan SA, Gonzales CS. Corneal Endothelial Cell Density and Morphology in Normal Filipino Eyes. Cornea 2004; 23(2):129-135.

14. Rao SK, Sen PR, Fogla R y cols. Corneal endothelial cell density and morphology in normal Indian eyes. Cornea 2000; 19:820–823.

15. Doughty MJ, Müller A, Zaman MI. Assessment of the Reliability of Human Corneal Endothelial Cell-Density Estimates Using a Noncontact Specular Microscope. Cornea 2000; 19(2):148-58.