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Órgano Oficial del Colegio Mexicano de Alergia, Asma e Inmunología Pediátrica y de la Asociación Latinoamericana de Pediatría

2008, Number 1

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Alerg Asma Inmunol Pediatr 2008; 17 (1)

Prevalence of allergy in children with recurrent infection

Barzuna L, Abdelnour A, Alfaro-Bourrouet W, Porras Ó

Language: Spanish
References: 26
Page: 5-13
PDF size: 372.91 Kb.


ABSTRACT

It is difficult to establish a relationship between allergy and recurrent infection. Allergic patients make worse their clinic condition when they undergo viral respiratory infections, and, at the same time, infections promote the future development of allergic conditions. This study determined the presence of early allergic markers in children with recurrent respiratory infections of the airways. Twenty-one children with respiratory infection and 21 asthmatic patients were recruited; alt the patients recorded recurrent respiratory infections. Total IgE, interleukin 10 levels and allergen specific IgE were determined against dust mites, casein, dog and cat dander, egg, molds arid cockroach. An interview concerning epidemiological aspects about allergy risk was made. HIV serology, immunoglobulin levels and blood counting were performed for the recurrent infection children. All the test mentioned above were normal. Sensitization was found in 33% of children with recurrent infection, the allergens involved were Dermatophagoides pteronyssinus, Dermatophagoides farinae, egg and Blatella germanica antigens. In the asthmatic group sensitization was found in 67% of the patients against Dermatophagoides pteronyssinus, Dermatophagoides farinae, egg, Blatella germanica, Blomia tropicalis, cat dander and casein allergens. Total IgE concentration was high and IL-10 low in every patient studied. It was found an association with sensitization and familiar antecedents of allergy and upper respiratory infection. Other epidemiological factors did not show uniform associations for the patients studied. It was concluded that children with recurrent respiratory infection had early allergic markers which can predispose the future development of allergic diseases.


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